Stronghold For Cats

Stronghold is a topical treatment for cats and dogs that effectively protects against fleas, heartworms, ear mites, and certain types of intestinal worms. With a single monthly application, Stronghold provides comprehensive parasite control, ensuring the well-being of your pet.

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This product has multiple variants. The options may be chosen on the product page
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This product has multiple variants. The options may be chosen on the product page

Stronghold treats and prevents various parasite infestations in cats and dogs, including fleas, mites, and worms. It kills adult fleas, larvae, and eggs, and can be used to manage flea allergy dermatitis. It also prevents heartworm disease, treats ear mites, adult intestinal roundworms, and hookworms in cats, and adult roundworms in dogs. Additionally, it addresses biting lice in both cats and dogs, and sarcoptic mange in dogs. The solution is applied to the skin between the shoulder blades, where it is absorbed and distributed throughout the body. Dosage varies based on the animal’s weight, species, and type of parasite, with detailed instructions provided in the package leaflet.

Stronghold contains selamectin, an antiparasitic from the avermectin class. Selamectin activates chloride channels on the surface of parasite nerve and muscle cells, allowing chloride ions to enter and disrupting their electrical activity. This disruption leads to paralysis or death of the parasites.


  • Broad-Spectrum Protection: Targets multiple types of parasites including fleas, heartworms, ear mites, roundworms, and hookworms.
  • Convenient Application: Easy-to-use topical solution applied monthly.
  • Long-Lasting: Provides continuous protection for a full month.
  • Safe and Effective: Clinically tested and proven safe for cats when used as directed.

Is Stronghold Suitable for My Cat?

Stronghold is suitable for most cats, including kittens over six weeks of age. It is designed to be safe for use in various breeds and can be a good option for both indoor and outdoor cats. Always consult with your veterinarian to ensure it is appropriate for your cat’s specific needs and health conditions.

Dosage Schedule

Stronghold should be applied once a month. The dosage is based on the weight of the cat:

  • Cats weighing up to 5.5 lbs: 15 mg (0.25 ml)
  • Cats weighing 5.6 lbs to 15 lbs: 45 mg (0.75 ml)

What are the Side Effects of Stronghold?

Side effects of Stronghold are rare but may include:

  • Temporary hair loss at the application site.
  • Mild skin irritation.
  • Digestive issues such as vomiting or diarrhea.
  • In very rare cases, more severe reactions may occur. If you notice any adverse reactions, contact your veterinarian immediately.

What Precautions Must Be Taken?

  • Avoid Contact: Ensure the solution does not come into contact with your cat’s eyes or mouth.
  • Monitor After Application: Watch your cat for any signs of adverse reactions, especially within the first few hours after application.
  • Avoid Bathing: Do not bathe your cat within 24 hours before or after application to ensure the effectiveness of the product.
  • Consult Your Veterinarian: Always seek veterinary advice before starting any new treatment, especially if your cat is pregnant, nursing, or has pre-existing health conditions.

How Effective is Stronghold?

Stronghold is highly effective when used as directed. It starts killing fleas within 24 hours of application and provides protection against heartworms, ear mites, roundworms, and hookworms for a full month. Its efficacy is backed by clinical studies and it is widely recommended by veterinarians for comprehensive parasite control.


Is Stronghold a Good Flea Treatment for Cats?

Yes, Stronghold is considered an excellent flea treatment for cats. Stronghold (selamectin) is a highly effective prescription medication against a broad range of parasites, including fleas. It’s known for its rapid onset of action and sustained protection.

Which is Better: Frontline or Stronghold?

Both medications are effective, but they offer different levels of protection:

    • Frontline Plus primarily targets fleas and ticks.
    • Stronghold offers a wider spectrum of protection, including fleas, ear mites, heartworms, and intestinal worms.
    • The best choice depends on your cat’s individual needs.

What are The Side Effects of Stronghold on Cats?

Stronghold is generally well-tolerated by most cats, with mild application site reactions such as temporary hair loss or irritation being common. However, infrequent side effects may include lethargy, drooling, vomiting, or diarrhea.

How Often Can I Use a Stronghold on My Cat?

Stronghold is designed for monthly application to provide continuous protection from parasites.