Nexgard vs K9 Advantix II Comparison

Nexgard vs K9 Advantix II: Similarities

Nexgard and K9 Advantix II are both effective in targeting fleas and ticks, providing protection for your dog from these common parasites. Both treatments are designed for once-monthly administration, making it easy for pet owners to maintain a regular schedule and ensure ongoing protection.

Another similarity is that both Nexgard and K9 Advantix II are waterproof, meaning they remain effective even if your dog gets wet from activities like swimming or bathing. This feature makes them reliable for outdoor dogs or those that enjoy water-based activities.

Additionally, both products start acting quickly after administration. Nexgard begins killing fleas within 4 hours and ticks within 24 hours, while K9 Advantix II begins to kill fleas within 12 hours. Both treatments provide long-lasting protection for an entire month, ensuring your pet is safeguarded from infestations throughout the month.

What Are the Differences Between Nexgard and K9 Advantix II?

Nexgard and K9 Advantix II are both effective treatments for fleas and ticks, but they differ significantly in their mode of administration, coverage, and active ingredients.

The first major difference is how they are administered. Nexgard is an oral chewable tablet, which makes it a more appealing option for dogs that enjoy treats. On the other hand, K9 Advantix II is a topical solution applied directly to your dog’s skin, which may be better for pets that are resistant to taking oral medications.

In terms of protection, Nexgard primarily targets fleas and ticks, killing 100% of fleas within 24 hours and four types of ticks, including those that cause Lyme disease. K9 Advantix II provides broader coverage, as it not only kills fleas and ticks but also repels mosquitoes, biting flies, and lice. This additional mosquito repellent function is especially beneficial in areas prone to mosquito-borne diseases, which Nexgard does not address.

The active ingredients are also different between the two products. Nexgard contains afoxolaner, which works by disrupting the nervous systems of fleas and ticks, killing them after ingestion. K9 Advantix II uses a combination of permethrin, imidacloprid, and pyriproxyfen, which kill and repel fleas, ticks, and mosquitoes by contact, meaning the pests do not have to bite your dog to be affected.

Safety considerations also play a role in choosing between these treatments. Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs, while K9 Advantix II is safe for use on pregnant and nursing dogs. However, K9 Advantix II is toxic to cats, so it should be used with caution in households that have both dogs and cats.

If you need broad protection against fleas, ticks, mosquitoes, and biting insects, K9 Advantix II is the better option, especially for dogs in mosquito-heavy areas. However, if your main concern is fast, targeted flea and tick treatment, Nexgard’s chewable tablets provide quick relief and prevent Lyme disease. Ultimately, the best choice depends on your dog’s lifestyle, health status, and your household environment. Consult your veterinarian to determine the best treatment for your pet’s needs.

The table below provides a side-by-side comparison of Nexgard and K9 Advantix II, highlighting their key benefits and differences. By examining these features, you can confidently select the product that best meets your dog’s specific needs.

Feature	K9 Advantix II	Nexgard
Kills Fleas	Yes	Yes
Repels Fleas	Yes	No
Kills Flea Eggs and Larvae	Yes	Kills fleas before they can lay eggs
Kills Ticks	Yes	Yes
Repels Ticks	Yes	No
Repels Mosquitoes	Yes	No
Prevents Heartworm	No	No
Protects Against Other Parasites	Repels and prevents biting flies and kills chewing lice.	No
Waterproof	Yes	Yes – taken orally
How Long to Work	12 hours to kill fleas	4 hours to kill fleas and 24 hours to kill ticks
Taste	N/A	Beef Flavored
Active Ingredient	Permethrin, Imidacloprid, and Pyriproxyfen	Afoxolaner
Dosing	1 application per month	1 tablet per month
Application Type	Topical	Chewable Tablet
Age	Dogs 7 weeks and older, more than 4 lbs	Puppies 8 weeks and older, more than 4 lbs
Manufacturer	Bayer Animal Health	Boehringer Ingelheim
Safety	Don’t apply to cats	Not yet evaluated for use in breeding, pregnant, or lactating dogs
Side Effects	Skin irritation such as redness, scratching, or other signs of discomfort	Vomiting, diarrhea, lethargy, rare neurological effects
Duration of Effectiveness	30 days	35 days
Price	Moderate per dose	Moderate per dose
Clinical Studies	Demonstrated high effectiveness in clinical trials	Demonstrated high effectiveness in clinical trials
Storage Instructions	Store at room temperature between 39°F and 77°F	Store at room temperature 30°C (86°F) with excursions permitted up to 40°C (104°F).

To help pet owners make an informed choice, the following table provides pricing details for both Nexgard and Advantix II, including different dosages and quantities available at Anipetshop. This breakdown allows you to find the most cost-effective solution for your dog’s parasitic prevention needs.

Product	Dosage	Package Size	Price
NexGard
NexGard Chewables for Dogs 4-10 lbs	11.3 mg Afoxolaner	3 Chews	US$61.00
NexGard Chewables for Dogs 10.1-24 lbs	28.3 mg Afoxolaner	3 Chews	US$65.00
NexGard Chewables for Dogs 24.1-60 lbs	68 mg Afoxolaner	3 Chews	US$59.00

Does NexGard work as well as K9 Advantix?

Both Nexgard and K9 Advantix use pesticides to target fleas and ticks. Nexgard contains Afoxolaner and kills 100% of fleas within 24 hours, while K9 Advantix, which combines Permethrin, Imidacloprid, and Pyriproxyfen, starts killing fleas within 12 hours. Both are effective, but K9 Advantix begins working faster against fleas.

Which product is better for dogs with sensitive stomachs?

For dogs with sensitive stomachs, K9 Advantix may be the better choice compared to NexGard. NexGard, an oral treatment, often causes gastrointestinal issues like vomiting and diarrhea, which can be problematic for sensitive dogs. In contrast, K9 Advantix is a topical treatment that minimizes stomach-related side effects since it is applied externally, although it can still cause skin irritation or allergic reactions. Always consult a veterinarian before choosing a flea and tick preventative to ensure it suits your dog’s specific health needs.

Where can I buy Nexgard?

At Anipetshop, you can buy NexGard without a vet prescription. Anipetshop is an online retailer that specializes in pet medications, including flea and tick treatments. We offer a variety of products for dogs and cats, sourced from reputable manufacturers. Their platform allows you to purchase products conveniently, without the need for a prescription, making it easier to access essential pet medications. NexGard is available in different dosages to suit the size of your dog