Nexgard vs Revolution Comparison
Nexgard vs Revolution: Similarities
Nexgard and Revolution are both highly effective products designed to protect dogs from flea infestations and provide month-long protection. Both of these treatments help prevent re-infestations by killing adult fleas and ensuring ongoing control for the full month between doses. They are trusted by veterinarians and are widely used by pet owners looking for reliable solutions against fleas and ticks.
Another similarity is their water-resistant efficacy. Nexgard, being an oral treatment, remains effective even after your dog swims or bathes, and Revolution, though a topical solution, is waterproof once applied. This ensures that the protection continues uninterrupted, regardless of your dog’s activities.
Both products are also suitable for use in puppies. Nexgard can be given to puppies as young as 8 weeks old, provided they weigh at least 4 pounds, while Revolution can be used on puppies from 6 weeks old. This makes them both accessible options for starting parasite protection early in your dog’s life.
What Are the Differences Between Nexgard and Revolution?
One of the key differences between Nexgard and Revolution is their form of administration. Nexgard is a beef-flavored chewable tablet, designed to be eaten by your dog, making it a mess-free and enjoyable experience. Revolution, on the other hand, is a topical solution that is applied directly to the skin, requiring some effort to ensure the product is correctly administered.
In terms of parasite coverage, Nexgard focuses on fleas and four types of ticks, including those that cause Lyme disease, making it ideal for dogs that need protection from a variety of tick species. Revolution, however, provides broader protection by also covering heartworm prevention, ear mites, and internal parasites such as roundworms and hookworms, in addition to controlling fleas and certain types of ticks.
The speed of action is another area where they differ. Nexgard starts killing fleas within 4 hours of administration, while Revolution begins working within 12 hours. Nexgard is therefore a slightly faster option for flea treatment, whereas Revolution’s strength lies in its multi-parasite protection.
Finally, safety in specific groups also distinguishes these two products. Revolution has been tested and proven safe for use in breeding, pregnant, and lactating dogs, making it a more versatile option for pet owners with dogs in these categories. Nexgard, however, has not yet been evaluated for use in pregnant or lactating dogs, so caution is advised when using it in these cases.
The table below provides a side-by-side comparison of Nexgard and Revolution, highlighting their benefits and key differences. By reviewing these features, you’ll be able to choose the product that best suits your dog’s specific needs with confidence.
| Feature | Revolution | Nexgard |
| Kills Fleas | Yes | Yes |
| Kills Ticks | American Ticks | Yes |
| Kills Flea Eggs and Larvae | Stops development | Kills fleas before they can lay eggs |
| Repels Fleas | No | No |
| Repels Ticks | No | No |
| Prevents Heartworm | Yes | No |
| Other Parasites | Ear mites, hookworms, and roundworms | No |
| Repels Mosquitoes | No | No |
| How Long to Work | Begins to kill fleas within 12 hours | 4 hours to kill fleas, 24 hours for ticks |
| Taste | N/A | Beef flavored |
| Waterproof | Yes | Yes, since taken orally |
| Active Ingredient | Selamectin | Afoxolaner |
| Dosing | Once per month | 1 tablet per month |
| Application Type | Topical | Chewable tablet |
| Age | Dogs 6 weeks and older | Puppies 8 weeks and older, weighing more than 4 lbs |
| Manufacturer | Zoetis | Boehringer Ingelheim |
| Safety | Breeding, pregnant, and lactating dogs may use | Not evaluated for use in breeding, pregnant, or lactating dogs |
| Side Effects | Vomiting, diarrhea, lethargy, decreased appetite | Vomiting, diarrhea, lethargy, rare neurological effects |
| Duration of Effectiveness | 30 days | 35 days |
| Price | Moderate per dose | Moderate per dose |
| Clinical Studies | Demonstrated high effectiveness in clinical trials | Demonstrated high effectiveness in clinical trials |
| Storage Instructions | Store at room temperature 59-86° F (15-30° C). | Store at room temperature 30°C (86°F) with excursions permitted up to 40°C (104°F). |
To help pet owners make an informed choice, the following table provides pricing details for both Nexgard and Revolution, including different dosages and quantities available at Anipetshop. This breakdown allows you to find the most cost-effective solution for your dog’s parasitic prevention needs.
Attention: Prices below are for reference only and may change over time !
| Product | Dosage | Package Size | Price |
| NexGard | |||
| NexGard Chewables for Dogs 4-10 lbs | 11.3 mg Afoxolaner | 3 Chews | US$61.00 |
| NexGard Chewables for Dogs 10.1-24 lbs | 28.3 mg Afoxolaner | 3 Chews | US$65.00 |
| NexGard Chewables for Dogs 24.1-60 lbs | 68 mg Afoxolaner | 3 Chews | US$59.00 |
| Revolution | |||
| Revolution Topical Solution for Dogs 5.1-10 lbs | 120 mg Selamectin | 3 Doses | US$69.00 |
| Revolution Topical Solution for Dogs 10.1-20 lbs | 240 mg Selamectin | 3 Doses | US$72.00 |
| Revolution for Puppies & Kittens up to 5 lbs | 60 mg Selamectin | 3 Doses | US$55.00 |
Can Nexgard and Revolution be used together?
Yes! There will be no interaction between the two products, especially this far apart.
Which product is safer: Nexgard or Revolution?
Nexgard is the only FDA-approved treatment for preventing Lyme disease infections. However, while Revolution is deemed safe for pregnant and lactating pets, Nexgard has not been evaluated for use in these animals. Additionally, Nexgard chewable tablets are not suitable for cats, whereas Revolution can be used for both cats and dogs.
Where can I buy Revolution or Nexgard?
At Anipetshop, you can buy Revolution and NexGard without a vet prescription. Anipetshop is an online retailer that specializes in pet medications, including flea and tick treatments. We offer a variety of products for dogs and cats, sourced from reputable manufacturers. Their platform allows you to purchase products conveniently, without the need for a prescription, making it easier to access essential pet medications. Both Revolution and NexGard are available in different dosages to suit the size of your dog.
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Lily Watson is an author specializing in veterinary care in Australia. With a profound passion for animal welfare and a solid foundation in veterinary science, Lily has dedicated herself to disseminating valuable knowledge and information for both pet owners and professionals in this field.