Nexgard vs Credelio Comparison
Nexgard vs Credelio: Similarities
Nexgard and Credelio are both oral flea and tick treatments for dogs that are highly effective and easy to administer. These treatments come in the form of beef-flavored chewable tablets, making them convenient for pet owners and enjoyable for dogs. Both Nexgard and Credelio work by killing adult fleas and ticks, providing month-long protection against these parasites when administered on a monthly basis.
Both products are designed for use in puppies and dogs, with Nexgard being safe for puppies as young as 8 weeks that weigh at least 4 pounds, while Credelio is safe for puppies from 8 weeks of age that weigh at least 4.4 pounds. They are both waterproof since they are taken orally, so they remain effective even if your dog swims or gets wet frequently.
These treatments are widely used for controlling flea infestations and various species of ticks, helping to prevent tick-borne diseases like Lyme disease. Both Nexgard and Credelio are designed to be given once a month and can be used year-round for continuous protection.
What Are the Differences Between Nexgard and Credelio?
Nexgard and Credelio are both effective treatments for eliminating fleas and ticks, but they differ in their speed of action, active ingredients, and product availability.
One key distinction is the time it takes for each product to eliminate fleas and ticks. Nexgard begins killing fleas within 4 hours and eliminates ticks within 24 hours, while Credelio kills 100% of fleas within 12 hours and 98.7% of ticks within 8 hours. Although both are effective, they have slightly different timelines for achieving full efficacy.
The active ingredients also vary between the two. Nexgard contains afoxolaner, which disrupts the nervous system of fleas and ticks, leading to their death. Credelio, on the other hand, uses lotilaner, another isoxazoline-class drug that blocks GABA-gated chloride channels in parasites, resulting in their uncontrolled neuromuscular activity and eventual death. Both ingredients target fleas and ticks similarly but through slightly different mechanisms.
Another notable difference is product availability. Nexgard offers 3-month and 6-month supplies, providing pet owners the convenience of fewer purchases over time. Credelio is available in 1-month or 6-month supplies, meaning pet owners might prefer the flexibility of choosing a shorter-term supply.
Neither Nexgard nor Credelio has been evaluated for use in breeding, pregnant, or lactating dogs, and they are both formulated specifically for dogs, not cats. It’s important to note that both products should be used with caution in dogs with a history of seizures, as there is a small risk of neurological side effects.
In summary, if you’re looking for faster flea elimination and want protection against Lyme disease, Nexgard is an excellent choice, especially with its convenient 3-month supply option. However, if you prefer a slightly longer window for tick elimination and a flexible 1-month supply option, Credelio is also a highly effective option. Both products are safe and effective, but the best choice will depend on your dog’s specific needs, any pre-existing health conditions, and your preference for dosing schedules.
The table below offers a side-by-side comparison of Nexgard and Credelio, highlighting their benefits and key differences. By reviewing these features, you can confidently determine which product is best suited for your dog’s specific needs.
| Feature | Credelio | NexGard |
| Kills Fleas | Yes | Yes |
| Repels Fleas | No | No |
| Kills Flea Eggs and Larvae | No | Kills fleas before they can lay eggs |
| Kills Ticks | Yes | Yes |
| Repels Ticks | No | No |
| Repels Mosquitoes | No | No |
| Prevents Heartworm | No | No |
| Protects Against Other Parasites | No | No |
| Waterproof | Yes – taken orally | Yes – taken orally |
| How Long to Work | Kills 100% of fleas in 12 hours and 98.7% of ticks in 8 hours | 4 hours to kill fleas and 24 hours to kill ticks |
| Taste | Beef flavored | Beef flavored |
| Active Ingredient | Lotilaner | Afoxolaner |
| Application Type | Chewable Tablet | Chewable Tablet |
| Dosing | 1 tablet per month | 1 tablet per month |
| Age | Dogs 8 weeks and older, weighing at least 4.4 lbs | Puppies 8 weeks and older, weighing more than 4 lbs |
| Manufacturer | Elanco | Boehringer Ingelheim |
| Safety | Has not been evaluated for use in breeding, pregnant, or lactating dogs | Not yet evaluated for use in breeding, pregnant, or lactating dogs |
| Side Effects | Anorexia, elevated BUN, increased thirst, diarrhea | Vomiting, diarrhea, lethargy, rare neurological effects |
| Duration of Effectiveness | 30 days | 35 days |
| Price | Cheap per dose | Moderate per dose |
| Clinical Studies | Demonstrated high effectiveness in clinical trials | Demonstrated high effectiveness in clinical trials |
| Storage Instructions | Store 59° to 77° F, excursions are permitted between 41° to 104° F | Store at room temperature 30°C (86°F) with excursions permitted up to 40°C (104°F). |
To help pet owners make an informed choice, the following table provides pricing details for Nexgard, including different dosages and quantities available at Anipetshop. This breakdown allows you to find the most cost-effective solution for your dog’s parasitic prevention needs.
| Product | Dosage | Package Size | Price |
| NexGard Chewables for Dogs 4-10 lbs | 11.3 mg Afoxolaner | 3 Chews | US$61.00 |
| NexGard Chewables for Dogs 10.1-24 lbs | 28.3 mg Afoxolaner | 3 Chews | US$65.00 |
| NexGard Chewables for Dogs 24.1-60 lbs | 68 mg Afoxolaner | 3 Chews | US$59.00 |
Can Nexgard and Credelio be used on cats?
Both Credelio and NexGard offer protection against fleas and ticks for both dogs and cats.
The product of Nexgard for cats is Nexgard Combo, this product for cats provides protection against heartworms, hookworms, roundworms, and tapeworms, making it a comprehensive parasite control option for felines.
Is Nexgard or Credelio better for flea prevention?
Credelio effectively gets rid of fleas within 12 hours and eliminates 98.7% of ticks within 8 hours, while Nexgard kills fleas in 4 hours but takes 24 hours to eliminate ticks. Additionally, Nexgard is the only FDA-approved option for preventing Lyme disease infections. In terms of flea prevention, Nexgard works faster against fleas, but Credelio is also highly effective.
Which product starts working faster: Nexgard or Credelio?
Credelio begins killing fleas within 4 hours and eliminates over 99% of them within 8 hours of administration. Nexgard, on the other hand, takes up to 24 hours to kill all fleas. So, Credelio starts working faster than Nexgard.
Where can I buy Nexgard?
At Anipetshop, you can buy NexGard without a vet prescription. Anipetshop is an online retailer that specializes in pet medications, including flea and tick treatments. We offer a variety of products for dogs and cats, sourced from reputable manufacturers. Their platform allows you to purchase products conveniently, without the need for a prescription, making it easier to access essential pet medications. NexGard is available in different dosages to suit the size of your dog.
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Lily Watson is an author specializing in veterinary care in Australia. With a profound passion for animal welfare and a solid foundation in veterinary science, Lily has dedicated herself to disseminating valuable knowledge and information for both pet owners and professionals in this field.