Credelio Chewable Tablets For Cats – 6 Tablets

Name: credelio for cats without vet prescription - Anipetshop
Brand: Credelio
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Rating: 5.00 (1 reviews)

Rated 5 out of 5 based on 1 customer rating

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Pet Weight

2-4 Lbs
4.1-17 Lbs

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Description

Credelio CAT (lotilaner) is an oral isoxazoline chewable tablet manufactured by Elanco, formulated to deliver a minimum dose of 2.7 mg/lb (6 mg/kg) of lotilaner per administration. The 48 mg tablet addresses flea infestations and black-legged tick infestations in cats within this weight range on a monthly dosing schedule. Each package contains 6 chewable tablets, providing a full six-month supply.

Recommended for

Cats and kittens weighing 2.0 to 17.0 lbs, 8 weeks of age and older (flea treatment/prevention); 6 months of age and older for tick control.

Indication/Coverage

Credelio CAT is indicated for cats and kittens experiencing active infestations or facing ongoing exposure to the following ectoparasites:

Flea treatment and prevention: Kills adult fleas (Ctenocephalides felis) and prevents re-infestation for 30 days per dose in cats and kittens 8 weeks of age and older weighing at least 2.0 lbs.
Tick treatment and control: Kills Ixodes scapularis (black-legged tick) adults for 30 days per dose in cats and kittens 6 months of age and older weighing at least 2.0 lbs.

Key Benefits

The following clinical properties distinguish Credelio CAT within the isoxazoline class for cats in the 2.0 to 17.0 lb weight range:

Rapid flea kill: Lotilaner begins killing adult fleas within 6 hours of administration, reaching greater than 98% efficacy within 12 hours based on controlled laboratory data.
Sustained monthly protection: A single dose maintains greater than 98% flea-kill efficacy through day 30, with 100% effectiveness confirmed at days 60 and 90 in U.S. field studies.
Pre-lay flea elimination: Lotilaner kills adult fleas before egg deposition occurs, interrupting the reproductive cycle and reducing environmental flea burden after the first treatment.
Tick coverage: Credelio CAT demonstrated greater than 97% effectiveness against Ixodes scapularis 72 hours after administration or infestation across a 31-day study period.
Oral delivery: Administration via chewable tablet bypasses the handling and coat-contact requirements of topical spot-on formats, which some cats actively resist.
Broad age eligibility: Flea coverage is approved from 8 weeks of age, allowing early intervention in younger cats before flea infestations become established.
Systemic mechanism: Lotilaner inhibits GABA-gated chloride channels in insects and acarines, producing uncontrolled neuromuscular activity and parasite death without requiring direct skin contact for activity.
Field-confirmed efficacy: In a 90-day U.S. field study, cats with flea allergy dermatitis showed measurable improvement in erythema, papules, scaling, alopecia, and pruritus following elimination of the flea infestation.

Caution

Hazards to Humans

Keep Credelio CAT out of the reach of children. This product is not for human use. Avoid accidental ingestion; wash hands thoroughly with soap and water after handling the tablet or packaging. Keep away from food, beverages, and food preparation surfaces.

Hazards to Domestic Animals

Credelio CAT is for oral use in cats and kittens only. Do not administer to cats under 2.0 lbs or younger than 8 weeks of age (flea indication) or younger than 6 months (tick indication). Lotilaner belongs to the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures; use with caution in cats with a history of neurologic disorders. The safety of this product has not been established in breeding, pregnant, or lactating cats; consult a veterinarian before use in these animals. Store in a secure location away from other pets to prevent accidental ingestion or overdose.

Possible Side Effects

Monitor your cat after each monthly administration, particularly following the first dose when individual tolerability is not yet established.

Adverse reactions identified in U.S. field studies and post-approval reporting include the following, listed by system:

Gastrointestinal signs: Vomiting, diarrhea, and anorexia were reported in field study participants; weight loss occurred in 2.2% of treated cats compared to 1.8% in the control group.
Respiratory signs: Tachypnea (rapid breathing) and dyspnea were reported both in the field study and in post-approval experience.
Neurologic signs: Tremors, ataxia, and seizures have been reported in cats receiving isoxazoline-class drugs, including cats without a prior history of neurologic disorders.
Systemic signs: Lethargy, hyperthermia, hypersalivation, tachycardia, mydriasis, behavioral changes including hyperactivity and vocalization, and pruritus have been reported in post-approval experience.
Elevated renal markers: Two geriatric cats in the field study developed mildly elevated blood urea nitrogen (BUN) during the study period; one had suspected pre-existing kidney disease.

Foreign market post-approval data also include reports of hepatopathy, pancreatitis, immune-mediated hemolytic anemia, glomerulopathy, and anaphylactic reactions resulting in death. If any adverse reaction occurs following administration, contact a veterinarian promptly.

Direction

Credelio Chewable Tablets For Cats is given orally once a month. Administer the chewable tablet with food or within 30 minutes after feeding; bioavailability is reduced in the fasted state and food co-administration is required for adequate drug absorption. Offer the tablet by hand, place it in an empty bowl, or conceal it within a small amount of food. If the cat does not voluntarily consume the tablet, place it at the back of the mouth and close the jaw gently until the tablet is swallowed. In multi-cat households, administer each cat's dose separately and keep cats apart until each has fully swallowed its tablet to prevent accidental cross-dosing.

How to Open

Credelio CAT is packaged in a foil blister card. Open the package as follows:

Identify the individual blister containing the tablet intended for the current dose.
Tear along the perforated lines to separate the single-dose blister from the card if applicable.
Flip the blister card so the foil side faces upward.
Peel the foil backing from the corner of the blister to expose the tablet, then lift the tablet out of the plastic well.

how to open credelio chewable tablets for cats — How to Open Credelio Chewable Tablets For Cats

How to Administer

Confirm the cat's current body weight on the day of dosing, then select the tablet size that corresponds to that weight.
Offer the tablet with food or within 30 minutes after a meal to ensure adequate absorption.
Present the tablet by hand or in a small bowl; allow the cat to consume it voluntarily if it accepts the tablet.
If the cat does not consume the tablet voluntarily, place it at the back of the mouth and hold the jaw closed gently until swallowing occurs.
Observe the cat briefly to confirm the tablet has been swallowed and has not been spat out; if the full tablet is not ingested, administer a replacement dose with food.

Storage

Store at 15 to 25°C (59 to 77°F).
Excursions are permitted between 5 and 40°C (41 and 104°F).
Keep out of reach of children.
Do not use after the expiry date printed on the packaging; the expiry date refers to the last day of the stated month.
Store in the original packaging to protect the tablets until use.

Tips for Using

Administer with Food: Lotilaner bioavailability is reduced in the fasted state; give the tablet with a meal or within 30 minutes after feeding to ensure adequate absorption at the labeled dose.
Dose Once Monthly: Administer on a consistent calendar date each month without interruption. Year-round dosing maintains continuous flea and black-legged tick coverage without gaps between treatment cycles.
Do Not Alter the Tablet: Administer the chewable tablet whole. Breaking or modifying it before administration is not described or supported in Elanco's prescribing information for Credelio CAT.
Treat All Cats in the Household: Each cat should receive a dose appropriate for its individual body weight. Treating only one cat in a multi-cat household leaves a reservoir for ongoing flea transmission between animals.
Conceal in a Small Amount of Food: Wrap the tablet in a small portion of wet food or a soft treat to encourage voluntary consumption. Offer this portion first to ensure the full tablet is swallowed before the cat accesses the rest of the meal.
Use Manual Placement if Needed: Place the tablet at the back of the cat's mouth and hold the jaw closed until swallowing occurs. Elanco's field study data confirm this method was required for 52.6% of doses across the study population.
Confirm the Tablet Is Swallowed: Observe the cat immediately after dosing to verify the tablet has not been spat out. If the intact tablet is found, re-administer with food; if vomiting occurs shortly after dosing, consult a veterinarian before giving a replacement dose.
Expect Gradual Clearance with Active Infestations: Credelio CAT kills adult fleas before egg deposition, interrupting the reproductive cycle from the first dose. In households with an established flea population, complete environmental clearance takes time; continued monthly dosing addresses each new wave of emerging adults.

Product Name	Credelio Chewable Tablets For Cats
Target Weight	2.0 to 4.0 lbs (0.5 to 2.0 kg) and 4.1 to 17.0 lbs (> 2.0 to 8.0 kg)
Active Ingredients	Lotilaner 12 mg per tablet(2.0 to 4.0 lbs), Lotilaner 48 mg per tablet( 4.1 to 17.0 lbs)
Application Type	Chewable tablet
Administration Route	administer with food, Oral
Pack Sizes Available	1, 3, or 6 tablets per pack
Treatment Frequency	Once monthly
Effective Against	Adult fleas (Ctenocephalides felis); Ixodes scapularis (black-legged tick)
Minimum Age (Flea)	8 weeks
Minimum Age (Tick)	6 months
Storage	15 to 25°C (59 to 77°F); excursions permitted 5 to 40°C (41 to 104°F)

FAQs

1. My cat weighs 4.1 lbs exactly. Is the 48 mg Credelio CAT tablet the right choice?

Yes. The 48 mg tablet is appropriate for cats weighing 4.1 to 17.0 lbs, and a cat at exactly 4.1 lbs falls within this range. Weigh on the day of dosing to confirm current weight before administering. Cats still below 4.1 lbs on the treatment day should receive the 12 mg tablet instead. Credelio for Cats is available in two weight-based tablet sizes:

Credelio CAT 12 mg – for cats 2.0 to 4.0 lbs
Credelio CAT 48 mg – for cats 4.1 to 17.0 lbs

2. Is the 48 mg lotilaner dose safe for a cat at the lower end of this range, around 4.1 lbs?

Yes. The 48 mg tablet delivers approximately 11.7 mg/kg to a 4.1 lb (1.86 kg) cat, which exceeds the minimum labeled dose of 6 mg/kg and remains well below the upper threshold evaluated in Elanco’s safety study.

3. My cat just crossed from the 12 mg tablet range into the 48 mg range. Should I switch immediately?

Switch on the next scheduled dosing date once the cat’s weight has been confirmed above 4.0 lbs on the day of administration. Do not split a 48 mg tablet to approximate the lower dose; the correct tablet for the confirmed weight on dosing day is the appropriate choice. Weigh your cat each month if it is still in a growth phase.

4. What should I do if I miss a monthly dose of Credelio CAT for my 4.1 to 17.0 lb cat?

Administer the missed dose as soon as you remember, then resume monthly dosing from that new date. Do not double-dose. A lapse in dosing creates a gap in flea and tick coverage; if your cat has been exposed to fleas or ticks during the gap, examine for signs of infestation and consult a veterinarian if flea allergy dermatitis or tick attachment is suspected.

5. Why does Credelio CAT need to be given with food?

Lotilaner bioavailability is reduced in the fasted state. Elanco’s clinical pharmacology data confirm that food co-administration is required to achieve the drug concentrations necessary for efficacy; administering on an empty stomach risks subtherapeutic absorption and reduced flea or tick control.

6. Can I give Credelio CAT to my 4-month-old kitten weighing 5 lbs?

For flea treatment and prevention, yes: the product is approved from 8 weeks of age at 2.0 lbs or greater, so a 4-month-old kitten at 5 lbs meets both criteria. For black-legged tick control, Credelio CAT is approved from 6 months of age; tick efficacy in kittens under 6 months has not been evaluated by Elanco.

7. My cat has had a seizure in the past. Can she still receive Credelio CAT?

Lotilaner is an isoxazoline-class drug, and this drug class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures, even in cats without a prior neurologic history. For a cat with a known seizure history, use with caution and only after veterinary assessment of the risk-benefit profile for that individual animal.

8. What happens if another pet in the household accidentally ingests a Credelio CAT tablet?

Credelio CAT is formulated for cats only. If a dog ingests a Credelio CAT tablet, contact a veterinarian immediately; the product is not labeled for dogs and the safety profile in dogs has not been established for this formulation. Store the packaging in a secure location out of reach of all pets between doses to prevent accidental ingestion.

9. My cat vomited shortly after receiving the tablet. Does she need a replacement dose?

If vomiting occurs within a short period of administration and you observe the intact tablet in the vomit, a replacement dose should be given with food. If the tablet is not visible, contact a veterinarian for guidance on whether re-dosing is appropriate, as partial absorption may have occurred.

10. How do I know if Credelio CAT is working in a cat with flea allergy dermatitis?

In the U.S. field study, cats with flea allergy dermatitis showed measurable improvement in erythema, papules, scaling, alopecia, dermatitis, and pruritus as a direct result of flea elimination. Improvement in skin signs typically follows confirmed reduction of flea counts, which Credelio CAT achieved at 98.5% on day 30, and 100% on days 60 and 90 in the same study. If skin signs persist or worsen after two monthly doses, a veterinarian should assess whether the dermatitis has a concurrent or alternative cause.

1 review for Credelio Chewable Tablets For Cats – 6 Tablets

5.0

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Janet Newell
Verified Buyer

March 17, 2026

Excellent product and the price is great

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