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Interceptor Spectrum Tasty Chews for Dogs 8-25 Lbs (4-11 Kg)
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Description
Interceptor Spectrum Tasty Chews for Dogs 8-25 Lbs (4-11 Kg) delivers monthly broad-spectrum parasite prevention and treatment via a palatable oral chewable tablet combining milbemycin oxime and praziquantel. Each tablet in this weight band contains 5.75 mg milbemycin oxime and 57 mg praziquantel, formulated for dogs weighing between 8.1 and 25 lbs (approximately 4 to 11 kg). The product is approved for dogs and puppies from six weeks of age.
Recommended for
Dogs and puppies weighing 8.1 to 25 lbs (4 to 11 kg) from 6 weeks of age.
Indication/Coverage
For dogs suffering from, or at risk from, mixed parasitic infections, Interceptor Spectrum Tasty Chews covers the following indications:
- Heartworm prevention: Prevention of heartworm disease caused by Dirofilaria immitis, administered monthly to intercept larval development before adult worm establishment occurs.
- Roundworm treatment: Treatment and control of adult Toxocara canis and Toxascaris leonina infections in the gastrointestinal tract.
- Hookworm treatment: Treatment and control of adult Ancylostoma caninum infections; milbemycin oxime achieved 99.6% efficacy against naturally acquired hookworm in controlled FDA studies.
- Whipworm treatment: Treatment and control of adult Trichuris vulpis
- Tapeworm treatment: Treatment and control of adult Taenia pisiformis, Echinococcus multilocularis, and Echinococcus granulosus infections; praziquantel at 5 mg/kg reached 100% efficacy against all three species in FDA-submitted laboratory studies.
Key Benefits
The following properties reflect the clinical profile of this formulation for dogs in the 8.1 to 25 lbs range.
- Concurrent parasite elimination: A single monthly tablet addresses five parasite categories simultaneously, covering both nematodes via milbemycin oxime and cestodes via praziquantel without requiring additional dewormers.
- Confirmed heartworm efficacy: Six consecutive monthly doses achieved 100% prevention of adult immitis establishment in controlled laboratory infection studies submitted to the FDA under NADA 141-338.
- Nematocidal mechanism: Milbemycin oxime disrupts glutamate-gated chloride ion channels in invertebrate nerve and muscle tissue, producing irreversible paralysis in roundworm, hookworm, and whipworm at the adult stage.
- Cestocidal mechanism: Praziquantel increases tegumental membrane permeability in tapeworm cells, causing paralysis and gastrointestinal expulsion of adult Taenia and Echinococcus
- Broad weight-band coverage: This variant spans 8.1 to 25 lbs, covering a large portion of small to medium-breed dogs, including breeds that reach adult weight within this range and remain on the same tablet size for life.
- Chewable acceptance rate: In a field palatability study of 115 client-owned dogs, 108 accepted the chewable directly from the owner’s hand, reducing the need for manual pilling in dogs that resist tablet administration.
- Once-monthly schedule: A single oral dose every 30 days maintains continuous heartworm prevention coverage and controls gastrointestinal parasite burdens without requiring dose splitting or multiple administration events.
Caution
Hazards to Humans
Not for human use. Keep out of reach of children. Wash hands after handling the tablet. Avoid contact with eyes. Do not store alongside food, beverages, or animal feed.
Hazards to Domestic Animals
Administer orally only. This variant is labeled for dogs and puppies weighing 8.1 to 25 lbs (4 to 11 kg) from six weeks of age. Do not give to dogs below this weight threshold or below six weeks of age. Exercise caution in debilitated, aged, pregnant, or nursing dogs and seek veterinary assessment before dosing in these cases. Isolated instances of individual sensitivity to milbemycin oxime or praziquantel have been documented. Consult a veterinarian before co-administering with other antiparasitic agents or drugs known to interact with macrocyclic lactones.
Possible Side Effects
Monitor your dog in the period following each monthly administration, particularly after the initial dose.
At the labeled dose, adverse reactions were not observed in field acceptability studies; however, the following signs have been documented across safety and efficacy studies at standard and supratherapeutic doses.
- Gastrointestinal reactions: Vomiting was recorded across multiple laboratory cohorts, including one dog in the field palatability study that vomited immediately after accepting the tablet. Soft feces and diarrhea occurred with broadly similar frequency in both treated and control groups at standard dosing levels.
- Systemic neurological signs (supratherapeutic doses): Ataxia, decreased activity, salivation, and tremors appeared at 3 and 5 times the maximum labeled dose in safety studies, presenting within the first 24 hours and resolving spontaneously without intervention. At the 1x labeled dose in a puppy safety cohort, ataxia was recorded once in a single animal.
- Isolated post-dose findings: One dog in a tapeworm efficacy study exhibited abnormal leaning behavior within 24 hours of administration at the standard dose; this finding was not replicated across other study populations.
Direction
Interceptor Spectrum Tasty Chews is given orally, once per month. Offer the chewable tablet from the hand or place it in the dog's meal bowl; most dogs in this weight range consume it without resistance. Where multiple dogs share a household, separate them at dosing time to prevent cross-consumption of the wrong weight-band tablet. Do not divide or break the tablet to split the dose, as each chewable is intended to provide a complete dose for this weight range.How to Open
- Separate a single dose by tearing along the perforated lines.
- Find one corner of the blister unit.
- Carefully peel off the foil backing from that corner until it is fully removed. Avoid pressing on the chewable.
- Take the chewable out of the blister and give it to your dog as soon as the package is opened.
How to Administer
- Weigh the dog on the day of dosing to confirm it falls within 8.1 to 25 lbs before proceeding.
- Offer the tablet from an open palm for approximately 60 seconds. If consumed, administration is complete.
- If the dog does not take the tablet from the hand, place it in the food bowl with a small portion of food for 60 seconds.
- If the tablet remains uneaten, place it directly in the dog's mouth, hold the jaws closed briefly, and confirm the tablet is swallowed.
- Observe the dog for vomiting during the 10 to 30 minutes following dosing. If the tablet is expelled in this window, consult a veterinarian before re-dosing.
Storage
- Keep out of reach of children.
- Store below 30°C (86°F).
- Do not use after the expiry date printed on the packaging; the expiry date refers to the last day of the month indicated.
- Retain tablets in the original blister card to protect against moisture exposure between monthly doses.
Tips for Using
Consistent monthly administration and accurate weight verification are the two most consequential factors in maintaining full-spectrum parasite control for dogs in the 8.1 to 25 lbs range:- Perform a heartworm screening before starting treatment: Consult your veterinarian and have your dog tested for heartworms to confirm a negative result before giving the first dose.
- Administer with food: Give the chewable tablet during or immediately after a complete meal to maximize the absorption of the active ingredients.
- Ensure the tablet is chewed thoroughly: If needed, divide the chew into smaller pieces or mix it with a small amount of food to encourage proper chewing rather than swallowing it whole.
- Observe your dog after administration: Monitor your pet for approximately 10–30 minutes after dosing to make sure the tablet is fully consumed and not spat out, hidden, or vomited.
- Replace any incomplete dose: If your dog vomits shortly after administration or does not consume the entire tablet, provide a full replacement dose as soon as possible.
- Follow a consistent monthly schedule: Give the medication on the same date each month to maintain continuous protection against heartworms and other parasites throughout the year.
- Address missed doses promptly: If you are less than 15 days overdue, administer the missed dose immediately and continue with your regular monthly schedule.
- Consult your veterinarian after extended gaps: If more than 60 days have passed since the last dose, contact your veterinarian and consider retesting before restarting the medication.
- Store properly: Keep the medication in its original blister packaging and store it in a cool, dry location at room temperature (15°C–25°C / 59°F–77°F) to preserve its effectiveness.
| Product Name | Interceptor Spectrum Tasty Chews for Dogs 8-25 Lbs (4-11 Kg) |
|---|---|
| Target Weight | 8-25 lbs (4-11 kg) |
| Packing color | Green |
| Active Ingredients | Milbemycin oxime: 5.75 mg, Praziquantel: 57 mg |
| Application Type | Flavored chewable tablet |
| Administration Route | Oral administration |
| Pack Sizes Available | 3 or 6 chewable tablets per package |
| Treatment Frequency | Once monthly |
| Minimum Age | 6 weeks |
| Effective Against | – Heartworm (Dirofilaria immitis, prevention) |
| Storage | Below 30°C (86°F) |
| Manufacturer | Elanco |
FAQs
1. My dog weighs exactly 8 lbs. Which tablet size is correct?
The 8-25 lbs tablet (5.75 mg milbemycin oxime / 57 mg praziquantel) is appropriate from 8.1 lbs. Dogs that have not yet reached 8.1 lbs on the dosing day should remain on the 2-8 lbs tablet; do not advance the weight band early. Weigh on the day of dosing to confirm which variant applies. Dogs exceeding 25 lbs should move to the next weight-band tablet. Interceptor Spectrum is available in 3 other weight-based variants:
- Interceptor Spectrum Tasty Chews for Dogs 2-8 Lbs (Up to 4 Kg)
- Interceptor Spectrum Tasty Chews for Dogs 25-50 Lbs (11-22 Kg)
- Interceptor Spectrum Tasty Chews for Dogs 50-100 Lbs (22-45 Kg)
2. Is 5.75 mg milbemycin oxime safe for a dog at the lower end of this range, around 8-9 lbs?
At the labeled minimum rate of 0.23 mg/lb (0.5 mg/kg), an 8.1 lb dog receives approximately 5.75 mg milbemycin oxime, which is within the established safe and effective range confirmed across multiple FDA safety studies. In repeat-dose studies at 1x the label dose in puppies from six weeks of age, clinical signs were rare and self-limiting. Dogs with a history of seizures, neurological conditions, or known MDR1 gene mutation (prevalent in collies, Shetland sheepdogs, and related breeds) should be assessed by a veterinarian before milbemycin oxime administration.
3. My dog just crossed from 8 lbs to 8.5 lbs. Do I switch tablets immediately?
Switch to the 8-25 lbs tablet on the next dosing day once the dog’s weight is confirmed at 8.1 lbs or above. Do not skip a dosing month during the transition; continuing without a dose creates a gap in heartworm prevention that is not retroactively corrected by the following month’s administration.
4. What should I do if I miss a monthly dose of Interceptor Spectrum 8-25 Lbs?
Administer the missed dose as soon as the omission is identified, then resume the regular monthly schedule from that new date. Do not give two tablets within a short interval to compensate. If the gap coincides with a period of active mosquito exposure, consult a veterinarian regarding whether a heartworm antigen test is indicated before continuing prevention.
5. Can I use the 8-25 lbs tablet for a dog at the upper limit, 24-25 lbs?
Yes. The 8-25 lbs tablet is labeled through 25 lbs and delivers milbemycin oxime and praziquantel within the approved dose range at this weight. Once a dog’s weight exceeds 25 lbs on a dosing day, advance to the 25.1-50 lbs tablet to maintain correct per-kilogram dosing for both active ingredients.
6. Does this tablet treat all tapeworm species my dog might pick up?
Interceptor Spectrum covers adult Taenia pisiformis, Echinococcus multilocularis, and Echinococcus granulosus, each confirmed at 100% efficacy in separate FDA-submitted studies at the 2.28 mg/pound (5 mg/kg) praziquantel dose. It does not cover Dipylidium caninum, the flea tapeworm, which requires a separate praziquantel or epsiprantel treatment. If flea tapeworm segments are identified, consult a veterinarian for an appropriate targeted treatment.
7. My 12 lb dog is on a flea prevention product. Is it safe to give Interceptor Spectrum alongside it?
Interceptor Spectrum does not provide flea or tick coverage and is commonly used alongside topical or oral flea and tick products. Before combining any antiparasitic agents, verify there are no known interactions between milbemycin oxime and the specific flea product in use; consult a veterinarian if the dog is also receiving any other systemic medications.
8. How do I know if Interceptor Spectrum is eliminating the hookworm infection in my dog?
Hookworm clearance is confirmed by fecal flotation examination rather than visible signs. In FDA studies, milbemycin oxime achieved 99.6% reduction in adult Ancylostoma caninum counts within seven days of a single dose. If a follow-up fecal test four weeks after treatment still shows hookworm eggs, consult a veterinarian to assess whether reinfestation from the environment is occurring or whether a different hookworm species is involved.
9. Can Interceptor Spectrum be given to a nursing dog in the 8-25 lbs range?
The product label advises caution in pregnant and nursing animals. Administer to a nursing dog only after a veterinarian has assessed whether the benefit outweighs any potential risk of milbemycin oxime or praziquantel transfer through milk to nursing puppies. Do not make this determination without veterinary input.
10. What is the earliest age a puppy in this weight range can start Interceptor Spectrum?
The labeled minimum age is six weeks, provided the puppy has also reached at least 8.1 lbs. A puppy six weeks of age that has not yet reached the minimum weight for this tablet should not receive the 8-25 lbs chewable; use the 2-8 lbs variant if the puppy meets the 2 lbs minimum threshold for that size, or defer with veterinary guidance until the appropriate weight is reached.
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