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Advocate For Cats Over 9 lbs (over 4 kg)
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NO PRESCRIPTION NEEDED
Safe Over-The-Counter Product
AU
BASED IN AUSTRALIA
Tracked Delivery 7-14 Days
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GENUINE BRANDED PRODUCT
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Choose based on your cat's weight
Description
Advocate For Cats Over 9 lbs (Over 4 kg) is a topical spot-on solution containing imidacloprid (80 mg) and moxidectin (8 mg), manufactured by Elanco. Each 0.8 ml pipette is calibrated for cats in the over 9 lbs weight range. Advocate for cats delivers dual-mechanism parasite control: imidacloprid eliminates fleas on contact without requiring a bite, while moxidectin, a macrocyclic lactone, is absorbed systemically to target heartworm larvae, lungworms, ear mites, roundworms, and hookworms.
Recommended for
Cats weigh over 9 lbs (over 4 kg) from 9 weeks of age.
Indication/Coverage
Advocate for Cats Over 9 lbs (Over 4 kg) treats and prevents mixed parasitic infections in cats weighing over 9 lbs from 9 weeks of age. The following indications are covered:
- Flea infestation (treatment and prevention): Kills adult fleas (Ctenocephalides felis) on contact and prevents reinfestation for 4 weeks per application.
- Ear mite infestation (treatment): Eliminates Otodectes cynotis with a single topical dose applied to the base of the skull, not directly into the ear canal.
- Notoedric mange (treatment): A single dose treats Notoedres cati Cats with severe cases require concurrent supportive care, as Advocate alone may not prevent fatal outcomes in advanced infestations.
- Lungworm, Eucoleus aerophilus (treatment): A single dose targets adult stages of Eucoleus aerophilus (syn. Capillaria aerophila).
- Lungworm, Aelurostrongylus abstrusus (prevention): Monthly application prevents disease caused by L3/L4 larvae of Aelurostrongylus abstrusus.
- Lungworm, Aelurostrongylus abstrusus (treatment): Three consecutive monthly doses are required to treat established adult Aelurostrongylus abstrusus
- Lungworm, Troglostrongylus brevior (treatment): A single dose targets adult Troglostrongylus brevior.
- Eye worm (treatment): A single dose eliminates adult Thelazia callipaeda.
- Heartworm disease (prevention): Monthly application prevents infection by destroying L3 and L4 larvae of Dirofilaria immitis before they mature. Protection requires uninterrupted monthly dosing throughout mosquito season and for one month beyond the last exposure.
- Roundworm and hookworm (treatment): Targets immature adults and adults of Toxocara cati (roundworm) and Ancylostoma tubaeforme (hookworm).
- Flea allergy dermatitis: The product can be incorporated as part of a treatment strategy for flea allergy dermatitis when administered at monthly intervals.
Key Benefits
The following characteristics distinguish Advocate for Cats Over 9 lbs based on its labeled pharmacology and clinical profile:
- Suitable from 9 weeks of age: Kittens that have reached 9 weeks and weigh over 9 lbs (over 4 kg) are eligible for treatment, establishing parasite control early in development.
- Contact-kill flea action: Imidacloprid destroys fleas through direct contact with the treated skin and coat, meaning the flea does not need to bite the cat before the active ingredient takes effect.
- Broad internal parasite coverage: A single monthly application addresses heartworm larvae, lungworms (three species), roundworms, hookworms, and ear mites, reducing the need for separate oral dewormers.
- Topical administration: The spot-on format bypasses the gastrointestinal tract entirely, making it suitable for cats that refuse oral medications or experience vomiting with tablets.
- Monthly dosing schedule: One 0.8 ml pipette applied every 30 days maintains uninterrupted protection across all labeled indications for this weight range.
- 4-week flea prevention duration: Each dose prevents new flea infestations for a full 4 weeks, though pre-existing pupae in the household environment may continue to emerge for 6 weeks or longer depending on climatic conditions.
- Systemic moxidectin distribution: After topical application, moxidectin absorbs through the skin and reaches steady-state serum levels after four consecutive monthly treatments, providing consistent internal parasite suppression once the loading period is complete.
Caution
Hazards to Humans
Hazards to Humans: Avoid contact with skin, eyes, and mouth during application. Wash hands thoroughly after use. People with known hypersensitivity to benzyl alcohol, imidacloprid, or moxidectin should administer with caution. If eye contact or accidental ingestion occurs, seek medical attention immediately. Keep the product out of reach of children.
Hazards to Domestic Animals
Advocate for Cats Over 9 lbs is for external use only. Do not use on kittens under 9 weeks of age, and consult a veterinarian before treating cats under 1 kg, sick, debilitated, pregnant, or lactating animals. Do not administer concurrently with other macrocyclic lactone antiparasitics. Prevent the treated cat from licking the application site, and separate treated animals from untreated housemates until the site is dry. Imidacloprid is toxic to birds, especially canaries.
Possible Side Effects
Monitor your cat after each application of Advocate for Cats Over 9 lbs.
Dermal reactions: Transient pruritus (itching) at the application site is the most commonly reported adverse effect. Occasional erythema (redness) has also been documented. In rare cases, local hypersensitivity reactions develop at the site of application, and very rare reports include skin lesions at the application site.
Gastrointestinal signs: Vomiting has been reported at an uncommon frequency. The product tastes bitter, and salivation may occur if the cat licks the application site immediately after treatment. This oral reaction is not a sign of intoxication and typically resolves within minutes without intervention. Correct application at the base of the skull minimizes the likelihood of ingestion.
Systemic signs: In very rare cases, neurological signs have been observed following treatment, including transient tremors, dilated pupils with reduced pupillary reflex, and nystagmus. Behavioural changes such as lethargy, agitation, and loss of appetite have also been reported at very rare frequency.
If any side effects appear, including reactions not listed above, or if you suspect the product has not achieved the expected result, consult your veterinarian. There is no known specific antidote for Advocate; treatment of adverse reactions is symptomatic. Activated charcoal may be beneficial in the event of accidental oral ingestion.
Direction
Advocate For Cats Over 9 lbs (over 4 kg) is a topical spot-on solution applied directly to the skin at the base of the skull, where the cat cannot reach to lick. Apply the product only to healthy, intact skin. Take care to avoid the cat’s eyes, mouth, and ears during application. In households with multiple pets, keep the treated cat separate until the application site is fully dry to prevent other animals from licking the area, which may lead to excessive salivation or digestive upset.How to Open
- Remove one pipette from the blister pack.
- Hold the pipette in an upright position.
- Twist and pull off the cap.
- Reverse the cap and use the opposite end to twist and remove the foil seal from the pipette tip.
How to Apply
- Part the fur on the cat's neck at the base of the skull until the bare skin is visible. If the solution contacts only the fur rather than the skin, transdermal absorption is incomplete and efficacy is reduced.
- Place the tip of the pipette directly on the exposed skin.
- Squeeze the pipette firmly several times to empty the entire 0.8 ml contents onto the single application spot. Do not distribute the solution across multiple sites.
- Confirm that the pipette is fully emptied. A partially administered dose results in subtherapeutic concentrations for one or more of the labeled parasites.
- Dispose of the used pipette safely. Do not dispose via wastewater or household waste, as Advocate is dangerous to aquatic organisms. Consult your veterinarian or local waste authority for proper disposal guidance.
Storage
- Keep Advocate for Cats Over 9 lbs out of the sight and reach of children.
- Store below 30°C (86°F).
- Do not use the product after the expiry date stated on the label and carton; the expiry date refers to the last day of the stated month.
- No special light protection or refrigeration is required beyond the temperature threshold.
Tips for Using
- Apply at Bedtime: Administer the treatment right before your cat's longest sleep cycle to reduce scratching and rubbing at the application site.
- Set Calendar Alerts: Apply the dose on the exact same day every month to prevent gaps in heartworm and flea protection loops.
- Check Weather Forecasts: Avoid applying the treatment right before heavy rain if your cat goes outdoors, ensuring 24 hours of dry absorption.
- Touch Skin Directly: Part the fur completely until you see bare skin; applying the fluid onto the fur instead of the skin reduces efficacy drastically.
- Use a Single Spot: Apply the entire dose to one high spot at the base of the skull so the concentrated formula spreads evenly through the skin's lipid layer.
- Avoid Bathing Timing: Do not bathe or shampoo your cat for 48 hours before or 24 hours after application to avoid stripping essential skin oils.
| Product Name | Advocate 80 mg + 8 mg Spot-On Solution for Large Cats (Over 4 kg / Over 9 lbs) |
|---|---|
| Target Weight | Over 9 lbs (over 4 kg) |
| Packaging Color | Purple |
| Pipette Volume | 0.8 ml |
| Active Ingredients | Imidacloprid: 80 mg per pipette, Moxidectin: 8 mg per pipette |
| Key Excipients | Benzyl alcohol, 1 mg/ml butylhydroxytoluene (E 321; as antioxidant) |
| Application Type | Topical spot-on solution applied directly to the skin at the base of the skull |
| Appearance | Clear yellow to brownish solution |
| Administration Route | For external use only |
| Pack Sizes Available | 1-pack, 3-pack, or 6-pack pipettes (0.8 ml per pipette). Not all pack sizes may be marketed in every region. |
| Treatment Frequency | Monthly for fleas, heartworm prevention, lungworm prevention, roundworm, and hookworm. Single dose for ear mites, notoedric mange, Eucoleus aerophilus, Troglostrongylus brevior, and eye worm. Three consecutive monthly doses for established Aelurostrongylus abstrusus infection. |
| Effective Against | – Fleas (Ctenocephalides felis, adults and larvae) |
| Storage | Below 30°C (86°F). Do not use after the expiry date on the label. |
FAQs
1. My cat weighs exactly 4 kg (9 lbs). Should I use the small cat pipette or the Advocate for Cats Over 9 lbs pipette?
Cats weighing exactly 4 kg fall within the small cat range (up to 4 kg). The Over 9 lbs pipette is formulated for cats exceeding 4 kg. Weigh your cat on the day of purchase, and if the scale reads 4.0 kg or below, use the small cat pipette (0.4 ml).
2. Is the 80 mg imidacloprid and 8 mg moxidectin dose in the large cat pipette safe for a cat that barely exceeds 4 kg?
A 4.1 kg cat receives approximately 19.5 mg/kg imidacloprid and 1.95 mg/kg moxidectin from this pipette. Both values fall within the labeled range of 10 to 20 mg/kg imidacloprid and 1 to 2 mg/kg moxidectin. The manufacturer’s safety data confirms tolerability at up to 10 times the recommended dose with no adverse effects observed.
3. My cat was on Advocate for Small Cats but now weighs 4.5 kg. Do I switch to Advocate for Cats Over 4 kg (9 lbs) immediately or finish the remaining small cat pipettes first?
Switch to Advocate for Cats Over 9 lbs with the next scheduled dose. The small cat pipette delivers only 8.9 mg/kg imidacloprid to a 4.5 kg cat, which falls below the minimum therapeutic threshold of 10 mg/kg. Continuing with the smaller pipette results in underdosing across all labeled indications.
4. I forgot to apply Advocate this month. How do I resume the schedule, and has my cat lost heartworm protection during the gap?
Apply the missed dose as soon as you remember, then continue monthly dosing from that new date. A gap exceeding 30 days means larvae transmitted by mosquitoes during that window may have advanced beyond the stage moxidectin can eliminate. If your cat lives in a heartworm-endemic area and the gap exceeded one month, consult a veterinarian about testing before resuming treatment.
5. Can I use Advocate for Cats Over 9 lbs at the same time as a tick collar or a separate tick spot-on, since Advocate does not cover ticks?
Advocate does not contain any acaricide effective against ticks. The product label states that no other antiparasitic macrocyclic lactone should be administered concurrently. Tick products that do not contain macrocyclic lactones fall outside this specific contraindication, but consult your veterinarian before combining any two parasite treatments.
6. My cat shook during application and some of the solution landed on her fur instead of skin. Do I apply another full 0.8 ml pipette?
Do not apply a second full pipette immediately. A small amount on surrounding fur is normal and will partially transfer to skin through coat contact. If the majority of the dose clearly missed the skin, contact your veterinarian for guidance on reapplication timing, as two full pipettes in close succession could exceed the labeled dose range.
7. How soon after applying Advocate for Cats Over 9 lbs does flea kill begin, and how long before heartworm prevention is established?
Imidacloprid kills fleas on contact with the treated skin and coat without requiring a bite, with flea kill beginning within hours of application. Each monthly moxidectin dose eliminates L3/L4 Dirofilaria immitis larvae acquired since the previous application. Steady-state serum levels of moxidectin are reached after four consecutive monthly treatments.
8. Are side effects like salivation or lethargy more likely in a cat weighing just over 4 kg compared to one closer to 8 kg?
No documented evidence indicates that cats at the lower end of this weight range experience side effects more frequently. A 4.1 kg cat receives approximately 19.5 mg/kg imidacloprid compared to 10 mg/kg for an 8 kg cat, but both values fall within the labeled therapeutic range. Overdose testing at up to 10 times the recommended dose showed no adverse effects, though monitoring after the first application is still advisable.
9. I have a cat using Advocate for Cats Over 9 lbs and a kitten under 9 weeks in the same household. Can the kitten be harmed by grooming or contact with the treated cat?
Advocate is not approved for kittens under 9 weeks of age. If the kitten grooms the treated cat’s application site before it dries, it could ingest imidacloprid and moxidectin at a dose the manufacturer has not assessed for safety in that age group. Keep the treated cat separated from the kitten until the application site is completely dry.
10. What is the difference between buying a 3-pack and a 6-pack of Advocate for Cats Over 9 lbs?
Each pipette in both pack sizes is identical: 0.8 ml containing 80 mg imidacloprid and 8 mg moxidectin. A 3-pack covers 3 months of monthly dosing, while a 6-pack covers 6 months. For cats requiring year-round heartworm prevention, a 6-pack reduces the risk of coverage gaps caused by delayed reorders.
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