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Bravecto Spot-On For Cats 2.6-6.2 lbs (1.2-2.8 kg)
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NO PRESCRIPTION NEEDED
Safe Over-The-Counter Product
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BASED IN AUSTRALIA
Tracked Delivery 7-14 Days
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Description
Bravecto Spot-On for Cats (112.5 mg fluralaner) is a topical isoxazoline applied once every 12 weeks for sustained flea and tick control. A single tube delivers systemic fluralaner at a minimum dose of 40 mg/kg body weight, achieving flea kill within 8 hours of treatment.
Recommended for: Cats and kittens weighing 2.6 to 6.2 lbs (1.2 to 2.8 kg) from 6 months of age.
Indication/Coverage
For cats suffering from, or at risk from, parasitic infestations involving fleas and ticks:
- Flea treatment and prevention: Kills adult Ctenocephalides felis (cat flea) and prevents reinfestation; reduces live flea counts by over 98% within 12 hours of application, sustained for 12 weeks.
- Black-legged tick control: Treatment and control of Ixodes scapularis infestations, with over 94% effectiveness 48 hours post-infestation for 12 weeks.
- Asian longhorned tick control: Treatment and control of Haemaphysalis longicornis infestations, with over 94% effectiveness for 12 weeks.
- American dog tick control: Treatment and control of Dermacentor variabilis infestations, with over 98% effectiveness for 8 weeks post-dosing. Efficacy against this species is not maintained beyond 8 weeks.
Key Benefits
The following properties distinguish the clinical profile of Bravecto Spot-On for cats in the 2.6 to 6.2 lb weight range:
- Small cat suitability: Approved for cats and kittens from 2.6 lbs (1.2 kg) and 6 months of age, making it one of the few isoxazoline spot-on formulations with labeled use at this weight threshold.
- Broad ectoparasite coverage: A single dose addresses three tick species (I. scapularis, H. longicornis, D. variabilis) alongside C. felis fleas, covering the primary ectoparasites of concern for cats in U.S. regions.
- Systemic mechanism: Fluralaner is absorbed through the skin into systemic circulation and reaches peak plasma concentration between 7 and 21 days post-application; fleas and ticks ingest the compound during feeding rather than through contact with the coat.
- Rapid flea kill: Laboratory data show 100% flea kill at 8 hours post-treatment and over 98% reduction in live flea counts within 12 hours, including after re-infestation across the dosing interval.
- Extended dosing interval: One tube every 12 weeks replaces the monthly topical schedule required by most alternative flea products, reducing the frequency of handling for cats that are difficult to treat.
- Flea allergy dermatitis resolution: In field studies, sustained flea elimination led to documented improvement in erythema, alopecia, papules, scales, crusts and excoriation associated with flea allergy dermatitis.
- Topical format for medication-resistant cats: The spot-on application bypasses the palatability and dosing compliance issues that arise with oral or chewable formulations in cats that consistently refuse oral medication.
- Year-round dosing compatibility: Treatment may begin at any point in the calendar year and continue without interruption, with no seasonal restriction on initiation.
Caution
Hazards to Humans
Keep out of reach of children; store in original packaging to prevent accidental access. Avoid skin and eye contact during application; if eye exposure occurs, flush slowly with water and seek immediate medical advice if contact lenses are worn. Wash hands and any contacted skin with soap and water after use. This product is highly flammable; keep away from heat sources, open flame, and sparks. Do not eat, drink, or smoke while handling. Children should not contact the application site for at least 2 hours after dosing.
Hazards to Domestic Animals
For topical use only; oral ingestion should be avoided. This product is indicated for cats and kittens from 6 months of age and weighing 2.6 lbs (1.2 kg) or more. Safety has not been established in breeding, pregnant, or lactating cats; consult a veterinarian before use in these animals. Fluralaner belongs to the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats, including those without prior neurologic history. Use with caution in cats with a history of neurologic disorders.
Possible Side Effects
Monitor your cat for at least 48 hours following spot-on application, particularly after the first dose.
The following adverse reactions were recorded in clinical studies and post-approval reporting for the isoxazoline class (fluralaner):
- Application site reactions: Greasy, oily, or wet appearance at the application site is commonly observed; matting, clumping, or spiking of hair in the treated area was noted in safety studies at up to 5x the labeled dose.
- Gastrointestinal signs: Vomiting occurred in 7.6% of cats in the U.S. field study (n=224); diarrhea was reported in 4.9% and decreased appetite in 3.6% of treated cats over the 105-day study period.
- Dermal reactions: Pruritus affected 5.4% of fluralaner-treated cats in the field study; alopecia was reported in 4.9%, and scabs or ulcerated lesions in 2.2%.
- Systemic and neurologic signs: Ataxia was observed in two cats during field studies; post-approval reports include muscle tremors, hypersalivation, lethargy, behavioral changes (including hyperactivity, hiding, and vocalization), and generalized pruritus.
If any of these signs develop or do not resolve within 72 hours after application, consult a veterinarian.
Directions
Apply the entire contents of one tube directly to the skin at the base of the skull. Part the fur to ensure the solution contacts bare skin rather than coat. Avoid applying excessive solution that could pool and run off the cat. If runoff is a concern due to coat density, the dose may be split across two adjacent spots at the base of the skull. Keep children away from the application site for 2 hours post-dosing and separate treated cats from other household animals until the application site is dry.How to Open
The tube is sealed and requires the cap to be rotated before use. Follow these steps to open without removing the cap:- Remove the tube from the pouch immediately before use. Put on gloves before handling.
- Hold the tube at the crimped end with the capped tip pointing upward.
- Rotate the cap clockwise or counterclockwise one full turn until a breaking of the seal is felt. The cap is designed to remain on the tube during administration and should not be removed.
- Confirm the seal is broken before proceeding. The tube is ready to administer once resistance at the cap is no longer felt.
How to Administer
- Position the cat standing or lying flat with its back horizontal and its head accessible.
- Part the fur at the base of the skull to expose bare skin at the application site.
- Place the tube tip vertically against the exposed skin.
- Squeeze the tube steadily and apply the entire contents directly onto the skin. If the volume causes runoff, apply the remainder to a second spot immediately behind the first.
- Dispose of the empty tube and used pouch. Wash hands and any skin that contacts the solution with soap and water.
Storage
- Keep out of reach of children.
- Store below 86°F (30°C).
- Do not store above this temperature.
- Keep in the original pouch until immediately before use to protect from moisture.
- Check the expiry date printed on the packaging; the product should not be used after the last day of the month indicated.
Tips for Using
- Target the skull base: Place the tip at the exact base of the skull to prevent the cat from licking the wet fluid during grooming.
- Expose the skin: Part the fur completely until bare skin is visible so the liquid does not get trapped or wasted in the coat.
- Keep horizontal position: Ensure your cat is standing or lying down with a flat, horizontal back to stop the liquid from running off.
- Twist the cap: Turn the cap one full turn without trying to pull it off, as it is designed to stay on the tube.
- Enforce water restrictions: Keep the cat dry and avoid bathing for at least 2 days after application.
- Isolate multi-pet households: Separate treated cats from other animals until the application site is completely dry to prevent mutual grooming and accidental ingestion.
- Maintain continuous scheduling: Reapply the topical treatment precisely every 12 weeks to eliminate coverage gaps across flea lifecycles.
- Treat the environment: Vacuum carpets, wash pet bedding, and treat all other household animals simultaneously to clear out existing infestations.
- Avoid skin lesions: Do not apply the solution to broken skin, open wounds, or scabbed areas, as this impairs proper absorption.
| Product Name | Bravecto Spot-On for Cats 2.6-6.2 lbs (1.2-2.8 kg) |
|---|---|
| Target Weight | 2.6 – 6.2 lbs (1.2 – 2.8 kg) |
| Packaging Color | Yellow |
| Active Ingredients | Fluralaner: 112.5 mg |
| Key Excipients | Dimethylacetamide, glycofurol, diethyltoluamide, acetone |
| Application Type | Topical spot-on solution applied directly to skin at the base of the skull |
| Appearance | Solution in single-dose tube sealed in foil pouch |
| Administration Route | External (topical) use only |
| Pack Sizes Available | 1 tube or 2 tubes per carton |
| Treatment Frequency | Once every 12 weeks (every 8 weeks if Dermacentor variabilis exposure is a concern) |
| Effective Against | – Cat flea (Ctenocephalides felis, adult) |
| Storage | Below 30°C (86°F); store in original pouch; protect from moisture |
FAQs
My cat weighs exactly 2.6 lbs. Is the 2.6–6.2 lb tube appropriate?
The 112.5 mg tube is approved from exactly 2.6 lbs (1.2 kg). Cats that have not yet reached 2.6 lbs on the treatment day should not receive this tube; consult a veterinarian to determine whether dosing should be deferred. Weigh the cat on the day of application before opening the pouch. Bravecto Spot-On for Cats is available in two other weight-based variants:
- Bravecto Spot-On for Cats 6.2–13.8 lbs (2.8–6.25 kg)
- Bravecto Spot-On for Cats 13.8–27.5 lbs (6.25–12.5 kg)
My cat is 5.8 lbs and near the upper end of this range. Is 112.5 mg enough fluralaner?
Yes. The labeled minimum dose is 18.2 mg/lb (40 mg/kg). At 5.8 lbs, the 112.5 mg tube delivers approximately 19.4 mg/lb, which exceeds the minimum threshold. A cat at the exact upper boundary of 6.2 lbs receives 18.14 mg/lb, still within the label. Once the cat exceeds 6.2 lbs at the time of dosing, move to the 250 mg tube for the 6.2–13.8 lb range.
My cat just crossed from the previous weight range into 2.6–6.2 lbs. Should I switch tubes immediately?
Switch on the next scheduled dose, not mid-cycle. If the previous tube was administered within the last 12 weeks and the cat has only recently crossed into this weight band, complete the current dosing interval before moving to the 112.5 mg variant. Confirm the new weight on the day of the next dose.
I missed the 12-week dose. What should I do?
Apply the missed dose as soon as you notice. Do not apply two tubes to make up for the gap. Restart the 12-week interval from the date the missed dose was applied. Please note that Bravecto is not effective against American dog ticks (Dermacentor variabilis) beyond 8 weeks after dosing; therefore, protection against this species will not be maintained if the dosing interval is extended beyond this period.
Can Bravecto Spot-On be used on a 6-month-old kitten weighing 2.6 lbs?
Yes, provided the kitten is at least 6 months of age and weighs at least 2.6 lbs on the treatment day. Safety for kittens under 6 months has not been established, and the product has not been shown to provide 12-week efficacy in this age group. Both conditions (age and weight) must be met before dosing.
My cat has a history of seizures. Is fluralaner safe to use?
Fluralaner belongs to the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats, including those without prior neurologic history. Cats with a history of neurologic disorders represent an elevated risk population. Consult a veterinarian before using this product in a cat with a seizure history.
Does Bravecto Spot-On remain effective if my cat gets wet within 12 weeks?
Merck Animal Health has not formally evaluated the effectiveness of Bravecto Spot-On after bathing or water immersion. Avoid bathing within the first 48 hours of application to allow initial dermal absorption. Beyond that window, the evidence base for water impact on residual efficacy is not established by the manufacturer.
Is Bravecto safe to use alongside other medications my cat currently takes?
In a well-controlled field study, Bravecto was used concurrently with vaccines, anthelmintics, antibiotics, steroids, and sedatives without recorded adverse interactions. For cats on medications not covered in this list, particularly those affecting neurologic function, consult a veterinarian before combining treatments.
Can I use this tube on my pregnant or nursing cat?
The safety of Bravecto Spot-On has not been established in breeding, pregnant, or lactating cats. Do not administer to pregnant or nursing cats without prior veterinary clearance.
How do I know the tube is properly opened before applying?
The tube is ready when you feel the seal break after rotating the cap one full turn. The cap stays on the tube throughout application and should not be removed. If no resistance break is felt during rotation, do not proceed.
5 reviews for Bravecto Spot-On For Cats 2.6-6.2 lbs (1.2-2.8 kg)
| 5 star | 60% | |
| 4 star | 40% | |
| 3 star | 0% | |
| 2 star | 0% | |
| 1 star | 0% |
1-5 of 5 reviews
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I’m grateful for the peace of mind this product gives me as a cat owner.
It’s a small investment for the protection and comfort it provides my cat.
I’ve noticed a significant improvement in my cat’s skin and coat since using this treatment.
I’ve been using this spot-on treatment for several months now, and I’m consistently impressed by its effectiveness. It’s a convenient and reliable way to protect my cat from fleas and ticks, and I’ve noticed a significant reduction in the number of parasites on my cat since using it.
As a responsible cat owner, I know how important it is to keep my pet protected from parasites. This spot-on treatment has been a reliable and effective solution for me. It’s easy to apply, and I’ve noticed a significant improvement in my cat’s overall well-being since using it.