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Bravecto Plus Topical Solution for Cats 6.2-13.8 lbs (2.8-6.25 kg)
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NO PRESCRIPTION NEEDED
Safe Over-The-Counter Product
AU
BASED IN AUSTRALIA
Tracked Delivery 7-14 Days
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GENUINE BRANDED PRODUCT
Guaranteed original, factory sealed for safety
Choose based on your cat's weight
Description
Bravecto Plus Topical Solution for Cats 6.2-13.8 lbs (2.8-6.25 kg) delivers fluralaner (isoxazoline class) and moxidectin (milbemycin class) in a single bi-monthly spot-on application, addressing ectoparasite infestations and endoparasite infections simultaneously. Each tube contains 250 mg fluralaner and 12.5 mg moxidectin, manufactured by Merck Animal Health and approved by FDA under NADA #141-518.
Recommended for
Cats and kittens weighing 6.2–13.8 lbs (2.8–6.25 kg) from 6 months of age and older.
Indication/Coverage
For cats suffering from, or at risk from, mixed parasitic infections, the labeled indications for Bravecto Plus Topical Solution (6.2–13.8 lbs) are as follows:
- Heartworm prevention: Prevention of heartworm disease caused by Dirofilaria immitis larvae via systemic moxidectin activity, administered at 2-month intervals.
- Flea treatment and prevention: Treatment and prevention of flea infestations (Ctenocephalides felis); kills adult fleas; laboratory data confirm 100% flea kill within 12 hours and greater than 99% reduction in live flea counts maintained throughout the 2-month dosing window.
- Black-legged tick control: Treatment and control of Ixodes scapularis infestations for 2 months; laboratory studies demonstrate 98.1% or greater effectiveness at 48 hours post-treatment or infestation.
- American dog tick control: Treatment and control of Dermacentor variabilis infestations for 2 months; effectiveness exceeds 90% at 48 hours, with efficacy not demonstrated beyond the 2-month labeled period.
- Asian longhorned tick control: Treatment and control of Haemaphysalis longicornis infestations for 2 months; 98.1% or greater effectiveness confirmed at 48 hours in controlled laboratory studies.
- Gulf Coast tick control: Treatment and control of Amblyomma maculatum infestations for 2 months; 100% effectiveness demonstrated at 72 hours, with no data supporting efficacy beyond the 2-month interval.
- Intestinal roundworm treatment: Treatment of Toxocara cati infections targeting 4th-stage larvae, immature adults, and adults.
- Intestinal hookworm treatment: Treatment of Ancylostoma tubaeforme infections targeting 4th-stage larvae, immature adults, and adults.
Key Benefits
The points below are drawn from Merck Animal Health’s prescribing information and controlled laboratory study data for this specific variant.
- Weight band accuracy: The 6.2 – 13.8 lbs (2.8 – 6.25 kg) tube delivers a minimum dose of 40 mg/kg fluralaner and 2 mg/kg moxidectin at the lower weight boundary, consistent with the labeled minimum therapeutic threshold across the full range.
- Concurrent parasite coverage: One application targets fleas, four tick species, heartworm larvae, intestinal roundworm, and intestinal hookworm, eliminating the need to administer a separate monthly oral endoparasite preventative.
- Transdermal systemic absorption: Both active compounds absorb through the skin and act systemically; fluralaner reaches peak plasma concentration between 3 and 21 days post-application, while moxidectin peaks between 1 and 5 days.
- Rapid flea kill onset: In controlled laboratory studies, Bravecto Plus killed 100% of fleas within 12 hours of treatment and sustained greater than 99% reduction in live flea counts for the full 2-month period.
- Extended 8-week dosing interval: A single tube provides labeled coverage for 2 months across all indicated parasites, which is distinct from the monthly administration schedule required by most oral and topical combination products.
- Multi-stage worm coverage: Moxidectin acts against Toxocara cati and Ancylostoma tubaeforme at larval, immature adult, and adult stages, reducing the timeframe during which re-established worm burdens can mature.
- Topical route for resistant cats: Spot-on administration bypasses the compliance barrier presented by oral chewables in cats that refuse or expectorate tablets.
- No absolute contraindications on label: The FDA-approved prescribing information states there are no known contraindications for this product; however, cats with neurologic history require veterinary assessment before administration due to the isoxazoline class association with tremors, ataxia, and seizures.
Caution
Hazards to Humans
Not for human use. Keep out of children’s reach; do not allow children to contact the application site for 2 hours post-application. Avoid skin and eye contact; flush eyes with water if exposure occurs and seek medical attention if contact lenses are worn. Wash hands with soap and water immediately after handling. The formulation is highly flammable.
Hazards to Domestic Animals
Bravecto Plus is for topical use in cats only and must not be ingested. This variant is formulated for cats weighing 6.2 – 13.8 lbs (2.8 – 6.25 kg) that are at least 6 months of age; cats outside these parameters should not receive this tube. Safety has not been established in breeding, pregnant, or lactating cats; use in these animals requires veterinary assessment. Fluralaner, an isoxazoline-class compound, has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats, including those with no prior neurologic history. Cats confirmed or suspected heartworm-positive require veterinary evaluation before treatment.
Possible Side Effects
Monitor your cat after each application, particularly within the first 48 hours, as the majority of adverse events documented in post-approval experience reports occurred within this window.
The following reactions are drawn from the controlled U.S. field study (135 cats, 120-day observation period) and post-approval adverse drug experience reporting to FDA/CVM, presented in decreasing order of reporting frequency:
- Application site alopecia: Localized hair loss at the dosing site; documented in both the field study and post-approval reports; self-limiting in most cases.
- Hypersalivation: Occurs when cats groom the application site before the solution has fully absorbed; driven by the formulation’s taste rather than systemic toxicity, and resolves once grooming access is interrupted.
- Vomiting: Reported in 5.9% of cats in the Bravecto Plus group during the field study, compared to 12.2% in the active control group; generally transient.
- Lethargy: Observed in 3.7% of treated cats in the field study; the active control group showed a higher incidence of 9.8%, suggesting the reaction is not product-specific in most cases.
- Diarrhea: Occurred in 3.7% of Bravecto Plus-treated cats versus 7.3% in the control group over the 120-day period.
- Elevated ALT: Alanine aminotransferase values greater than twice the upper reference range (100 IU/L) were recorded in 3.0% of treated cats, with concurrent mild AST elevation; no associated clinical signs of liver disease were noted in affected animals.
- Neurologic signs (rare): Tremors, ataxia, and seizures have been reported with isoxazoline-class medications in cats, including animals without a documented neurologic history. Discontinue use and contact a veterinarian immediately if any of these signs develop.
- Post-approval foreign market reports (within 48 hours): Periorbital swelling, erythema, behavioral changes including aggression and hyperactivity, mydriasis, excessive grooming, pyrexia, and alopecia have been reported voluntarily.
Direction
Bravecto Plus Topical Solution for Cats 6.2-13.8 lbs (2.8-6.25 kg) is applied as a topical spot-on at the base of the skull, positioned where the cat cannot reach to self-groom the wet site. Squeeze the entire tube contents onto exposed skin in one application; if volume is sufficient to cause run-off, a second spot applied slightly caudal to the first is acceptable per label instructions. Keep the cat separated from other household cats for at least 2 hours after dosing to prevent inter-cat grooming of the application site. Avoid contact with the cat's eyes during and after application.How to Open
- Remove the tube from the foil pouch immediately before use; opening the pouch in advance exposes the formulation to moisture.
- Put on gloves before handling the tube.
- Hold the tube at the crimped end with the cap pointing upward, tip directed away from you.
- Rotate the cap one full turn clockwise or counterclockwise until the seal breaks; the cap remains on the tube during dosing and should not be pulled off.
How to Administer
- Position the cat standing or lying flat with the back horizontal; this keeps the application site level and reduces solution run-off.
- Part the fur at the base of the skull firmly to expose bare skin; the tube tip must make contact with skin, not the coat.
- Place the tube tip vertically against the exposed skin surface.
- Squeeze steadily and deposit the entire tube contents directly onto the skin. If run-off occurs, apply the remaining volume to a second spot slightly behind the first.
- Dispose of the empty tube and foil pouch according to local waste regulations. Prevent the cat and other animals from contacting the wet site for a minimum of 2 hours post-application.
Storage
Store out of reach of children. Maximum storage temperature is 25°C (77°F); do not expose to higher temperatures. Keep in the original foil pouch to protect against moisture. Open the pouch only immediately before dosing. Do not administer after the expiry date printed on the carton; the stated expiry date refers to the final day of that calendar month.Tips for Using
- Apply at the back of the head: Place the solution directly on the skin at the base of your cat’s skull. This area is difficult for cats to reach when grooming, helping prevent accidental licking of the product.
- Expose the skin completely: Gently part the fur until the skin is clearly visible. Applying the medication directly to the skin ensures optimal absorption and effectiveness.
- Keep your cat in a level position: During application, make sure your cat is standing or lying comfortably with its back straight. This helps keep the liquid from running down the neck or onto the fur.
- Open the tube properly: Hold the applicator upright and twist the cap one complete turn without removing it. A slight click indicates that the seal has been punctured and the tube is ready for use.
- Keep the coat dry after treatment: Avoid bathing, shampooing, or allowing your cat to become wet for at least 3 days following application. Moisture may reduce the effectiveness of the medication before it is fully absorbed.
- Prevent contact with other pets: If you have multiple animals, keep the treated cat separated until the application site is completely dry. This helps avoid accidental grooming, ingestion, or transfer of the product.
- Inspect the application area first: Apply only to healthy, intact skin. Do not use the product on areas affected by wounds, irritation, open sores, or damaged skin.
- Use immediately after opening: Leave the pipette sealed in its protective packaging until you are ready to apply the treatment. Opening it too early may affect product stability and performance.
- Stay on a consistent treatment schedule: Continue applying the medication according to your veterinarian’s recommendations, which is commonly every two months for heartworm prevention.
- Handle missed doses appropriately: If a scheduled treatment is missed, apply the medication as soon as possible to maintain protection. Avoid administering an extra dose to compensate for uncertainty about a previous application.
| Product Name | Bravecto Plus Topical Solution for Cats 6.2–13.8 lbs |
|---|---|
| Target Weight | 6.2 – 13.8 lbs (2.8 – 6.25 kg) |
| Packaging Color | Blue |
| Active Ingredients | Fluralaner: 250 mg, Moxidectin: 12.5 mg |
| Key Excipients | Dimethylacetamide, glycofurol, diethyltoluamide, acetone, butylhydroxytoluene |
| Application Type | Topical spot-on solution applied directly to the skin at the base of the skull |
| Appearance | Clear solution |
| Administration Route | For external (topical) use only |
| Pack Sizes Available | 1 or 2 tubes per carton |
| Treatment Frequency | Every 2 months |
| Effective Against | – Fleas (Ctenocephalides felis, adults) |
| Storage | Below 25°C (77°F); keep in original foil pouch; protect from moisture |
FAQs
1. My cat weighs exactly 6.2 lbs today. Is the 6.2–13.8 lbs tube the right choice?
The 6.2–13.8 lbs tube (250 mg fluralaner / 12.5 mg moxidectin) is appropriate for cats weighing more than 6.2 lbs (2.8 kg) on the day of dosing. Cats weighing exactly 6.2 lbs or below should receive the 2.6–6.2 lbs variant (112.5 mg fluralaner / 5.6 mg moxidectin); do not administer this tube to a cat at or below the 6.2 lbs boundary. Weigh on dosing day to confirm. Cats exceeding 13.8 lbs (6.25 kg) should move to the next variant. Bravecto Plus is available in two other weight-based variants:
2. Is 250 mg of fluralaner safe for a 6.3 lb cat at the bottom of this weight band?
At 6.3 lbs, a cat receiving 250 mg fluralaner receives 39.68 mg/lb, well above the labeled minimum therapeutic dose of 18.2 mg/lb. Merck Animal Health’s margin-of-safety studies administered up to 5 times the maximum labeled dose in kittens with no clinically relevant treatment-related effects observed. The dose delivered at the lower weight boundary of this variant is within the evaluated safety range.
3. My cat just grew past 6.2 lbs and moved out of the 2.6–6.2 lbs range. Do I switch tubes at the next dose?
Switch to the 6.2–13.8 lbs tube at the next scheduled application. Continuing with the smaller tube once the cat exceeds 6.2 lbs results in underdosing below the 18.2 mg/lb (40 mg/kg) fluralaner threshold, which compromises efficacy against all labeled parasites. There is no clinical reason to complete a smaller-dose pack once the weight boundary has been crossed.
4. What happens if I miss the 8-week application date for this product?
Apply the missed dose as soon as the gap is noticed, then reset the 8-week schedule from that new application date. The product label states explicitly that if a 2-month interval is exceeded, the dose should be administered immediately and the every-2-months schedule resumed. Any gap longer than 2 months between doses means heartworm prevention against Dirofilaria immitis larvae cannot be guaranteed for the unprotected period.
5. Can I bathe my cat shortly after applying Bravecto Plus?
The effectiveness of Bravecto Plus after bathing or water immersion has not been evaluated, as stated in the FDA-approved label. Avoid bathing or allowing water immersion in the days immediately following application. Make sure the animal’s coat is completely dry before applying the dose to ensure the skin is dry at the time of administration.
6. My cat has a history of seizures. Can she still use Bravecto Plus?
Fluralaner belongs to the isoxazoline class, which is associated with neurologic adverse reactions including tremors, ataxia, and seizures. The product label notes these reactions have been reported even in cats with no prior neurologic history. Cats with a documented seizure history require veterinary assessment before any isoxazoline-class product is administered; this is not a decision that should be made based on label guidance alone.
7. Is Bravecto Plus safe for a pregnant or nursing cat in this weight range?
The FDA-approved label states that safety has not been established in breeding, pregnant, or lactating cats. Until controlled data are available, use in these animals should be deferred unless a veterinarian determines the clinical benefit outweighs the uncharacterized risk for that individual cat.
8. Does Bravecto Plus in this weight range protect against all ticks my cat might encounter outdoors?
Bravecto Plus has demonstrated labeled efficacy against four tick species: Ixodes scapularis, Dermacentor variabilis, Haemaphysalis longicornis, and Amblyomma maculatum. It is not labeled for Amblyomma americanum (lone star tick) or Rhipicephalus sanguineus (brown dog tick). Cat owners in areas where these unlabeled species are present should discuss supplementary tick control options with a veterinarian.
9. Can I use Bravecto Plus alongside flea shampoo or another topical product?
The controlled U.S. field study showed no adverse reactions when Bravecto Plus was used concurrently with vaccines, antibiotics, anthelmintics, and corticosteroids. Concurrent use with other topical products was not evaluated in this study. For cats already receiving a separate topical treatment, confirm compatibility and timing with a veterinarian before combining products, as overlapping applications to the same skin area may alter absorption.
10. How quickly will Bravecto Plus start controlling fleas on my 10 lb cat?
In controlled laboratory studies, Bravecto Plus killed 100% of fleas within 12 hours of initial application and maintained greater than 99% reduction in live flea counts within 12 hours of treatment or re-infestation for the full 2-month period. Fluralaner acts systemically after transdermal absorption; fleas are exposed when they bite the treated cat, so the product does not function as a repellent before contact occurs.
6 reviews for Bravecto Plus Topical Solution for Cats 6.2-13.8 lbs (2.8-6.25 kg)
| 5 star | 83% | |
| 4 star | 16% | |
| 3 star | 0% | |
| 2 star | 0% | |
| 1 star | 0% |
1-5 of 6 reviews
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Excellent customer service, ordered for the UK as this is a vet prescribed medication only, same cost as a UK vet, shipped straight away and arrived within 1 week – very please with the product and the service and shipping
Since using this product, my cat has been free from fleas, ticks, and ear mites.
I appreciate how easy it is to apply this medication to my cat every month.
This topical solution has kept my cat safe from heartworms and other parasites without any fuss.
I was impressed by how effective this topical solution is against both fleas and ticks. My cat has been parasite-free since we started using it, and the application is so straightforward. It’s a relief to know she’s protected from heartworms as well.