Description
Valuheart Monthly Heartworm Tablets (45–88 lbs / 21–40 kg) contain 240 mcg ivermectin per tablet, formulated to meet the 6 mcg per kg bodyweight minimum dose across the full 21–40 kg range. Each tablet in this variant is color-coded yellow, setting it apart from the blue (up to 22 lbs) and green (23–44 lbs) formulations. Registered under APVMA number 66288/53261 and manufactured by Value Plus Animal Health Care Products, this single-ingredient oral preventive targets heartworm larvae exclusively.
Recommended for
Dogs weighing 45–88 lbs (21–40 kg) from 6 weeks of age.
Indication/Coverage
For dogs suffering from, or at risk from, heartworm infection:
- Prevention of heartworm disease: Eliminates tissue-stage larvae of Dirofilaria immitis that infect the dog during the 30-day period before each monthly dose. This product does not eliminate or affect established adult heartworms.
Key Benefits
The yellow Valuheart tablet is formulated to address the specific dosing requirements of large-breed dogs within the 21–40 kg range:
- Large-Breed Dose Precision: Each yellow tablet delivers 240 mcg of ivermectin and is formulated for dogs weighing 21–40 kg. A single tablet provides the recommended heartworm-prevention dose across this labeled weight range without requiring tablet splitting.
- Monthly Larval Clearance: One dose per month eliminates D. immitis L3 and L4 larvae acquired during the preceding 30 days, preventing their development into adult heartworms.
- Extended Entry Window: Dogs starting prevention for the first time may begin up to 4 months after initial mosquito exposure and still achieve heartworm control, provided monthly dosing is maintained for at least 12 months.
- Age Eligibility from 6 Weeks: The product is labeled from 6 weeks of age, applicable to large-breed puppies that reach the 21 kg threshold early in development.
- Breeding Animal Safety: Label data confirm no adverse effects in stud dogs, pregnant bitches, or lactating females at the standard dose, with no adjustment required for reproductive status.
- Oral Delivery Options: The tablet accepts hand-feeding, food incorporation, or treat concealment, giving owners flexibility with large dogs that may resist topical application handling.
Caution
Hazards to Humans
Keep out of reach of children. Wash hands thoroughly after handling tablets or contact with the dog’s saliva shortly after dosing. If accidental ingestion occurs, seek medical attention promptly. Do not allow children to handle tablets unsupervised.
Hazards to Domestic Animals
Valuheart is for oral use in dogs only; do not administer to cats or any other species. This variant is labeled for dogs from 6 weeks of age weighing 21–40 kg. Dogs with no prior heartworm prevention history, or those returning after a lapse in their program, should be tested for adult heartworm and circulating microfilariae before commencing treatment, as this product does not eliminate established adult infections. Consult a veterinarian before administering to debilitated, aged, or underweight animals. Discontinue and seek veterinary assessment if unexpected reactions arise after dosing.
Possible Side Effects
Monitor your dog for at least 30 minutes after the first dose and following any administration to a dog with a history of potential mosquito exposure without prior prevention.
The following adverse reactions have been documented in clinical settings:
- Transient diarrhea: Recorded in dogs carrying circulating microfilariae at the time of dosing, resulting from a hypersensitivity response to dying microfilariae rather than a direct toxic effect of ivermectin at the labeled dose.
- Individual sensitivity: A small number of dogs may display atypical signs at the standard dose; if neurological disturbances, excessive salivation, or marked lethargy develop, cease administration and contact a veterinarian without delay.
Seek veterinary attention if any reaction fails to resolve within 24 hours or intensifies after the initial dose.













These heartworm tablets have made a huge difference in my dog’s health. They’re easy to administer, and I’m confident they’re doing their job.
I’m so glad I found these heartworm tablets for my dog. They’re easy to give, and they provide excellent protection.
My dog’s health is in good hands with Valuheart.
Finding reliable heartworm prevention without a vet prescription is tough, but Anipetshop made it easy. These tablets are perfect for my dog.
Searching for heartworm prevention without a vet’s prescription was frustrating, but Anipetshop came through for me. These tablets are excellent.