Comfortis Plus is an advanced parasitic treatment for dogs, targeting fleas, heartworms, and intestinal worms such as roundworms, hookworms, and whipworms. Safe for puppies as young as 8 weeks old and weighing at least 3.3 pounds, it provides comprehensive protection with a single monthly dose. This treatment demonstrates rapid effectiveness against fleas, achieving full efficacy within hours. Additionally, it boasts significant efficacy against heartworms and intestinal worms, ensuring your dog remains free from harmful parasites. Regular monthly administration ensures your dog stays healthy and protected.
Comfortis Plus contains two active pharmaceutical ingredients: spinosad and milbemycin oxime. Spinosad works by causing excitation of the insect’s nervous system, leading to its death. Milbemycin oxime interferes with the parasite’s nerve transmission, effectively preventing heartworm and treating intestinal worms.
Directions
- Check the weight of your dog before commencing treatment.
- Administer Comfortis Plus chewable tablet directly to your dog or mix it with the dog’s meal.
- Ensure your dog consumes the entire Comfortis Plus dose.
- Do not split the Comfortis Plus tablet; administer it whole.
- Dosage starts with a minimum dose of 13.5 mg/lb (30 mg/kg) of body weight.
- Treatment with Comfortis Plus can begin at any time during the year.
Dosage
Administer Comfortis according to the following dosage table:
| Dog’s Weight (lbs) |
Comfortis Plus Tablet Strength (mg) |
Pack Color |
|
3.3 – 4.8 |
90 mg Spinosad / 0.45 mg Milbemycin Oxime | Pink |
|
4.9 – 9.9 |
140 mg Spinosad / 0.7 mg Milbemycin Oxime |
Orange |
|
10.0 – 19.9 |
270 mg Spinosad / 1.35 mg Milbemycin Oxime |
Green |
| 20.0 – 39.9 |
560 mg Spinosad / 2.8 mg Milbemycin Oxime |
Blue |
|
40.0 – 59.9 |
810 mg Spinosad / 4.05 mg Milbemycin Oxime |
Brown |
| 60.0 – 120.0 | 1620 mg Spinosad / 8.1 mg Milbemycin Oxime |
Red |
Benefits
- Provides rapid effectiveness against fleas.
- A single dose prevents fleas, heartworms, and intestinal worms for a full month.
- Significantly reduces the number of fleas on dogs within hours.
- Prevents flea allergy dermatitis and improves signs of flea allergy dermatitis in dogs.
- No need for monthly administration or dealing with messy topical applications.
- Reduces gaps in protection against flea and worm infestations.
- The chewable tablet has a palatable taste, making it easy to administer.
- Treats various types of intestinal worms, including roundworms, hookworms, and whipworms.
Safety
- Comfortis Plus is strictly recommended for veterinary use only.
- Keep the product away from children.
- Do not eat, drink, or smoke while administering the product.
- After treatment, immediately wash your hands with soap and water.
- Store at a controlled room temperature of 59-86° F (15-30° C).
Warnings
- Before starting the treatment, consult your vet if your dog has a history of epilepsy or seizures.
- If your dog experiences vomiting, diarrhea, lethargy, or decreased appetite, contact a vet immediately.
- The safe use of Comfortis Plus in breeding, pregnant or lactating dogs has not been established.
FAQs
What happens if I miss giving a dose of Comfortis?
If you miss giving a dose of Comfortis, administer the missed dose as soon as you remember, with food. Then, resume the regular monthly dosing schedule.
What happens if I overdose my pet on Comfortis?
At doses up to 100 mg/kg body weight per day for 10 days, the only clinical symptom of overdose with Comfortis was vomiting, typically occurring within 2.5 hours of dosing. Mild elevations of ALT (alanine aminotransferase) were observed in all treated dogs, with values returning to baseline by day 24. In the event of an overdose, contact your veterinarian immediately. Symptoms of overdose may include severe vomiting, lethargy, and other adverse reactions more pronounced than usual side effects
What should I avoid while giving Comfortis?
Avoid giving Comfortis to dogs with a history of epilepsy without consulting your veterinarian. Additionally, avoid using Comfortis concurrently with high, extra-label doses of ivermectin, as this can increase the risk of neurological side effects
Can other medications be given while my dog is taking Comfortis?
Yes, COMFORTIS has been given safely with a wide variety of products and medications. Ensure your veterinarian is aware of all products you have administered or plan to administer to your dog. For heartworm prevention, use products specifically prescribed by your veterinarian.
Will my dog need to stay out of water with Comfortis to ensure it still works properly?
No, Comfortis is an oral medication and does not require any restrictions regarding water exposure. Your dog can swim or be bathed immediately after treatment without affecting the efficacy of the medication.
What are the potential side effects of Comfortis?
Potential side effects of Comfortis in dogs include vomiting, decreased appetite, lethargy, diarrhea, coughing, increased thirst, increased appetite, hyperactivity, excessive salivation, and redness of the skin. In rare cases, dogs may experience trembling, seizures, incoordination, and excessive dilation of pupils.