Simparica TRIO Chewable Tablets for Dogs 2.8-5.5 lbs (1.25-2.5 kg)

Simparica TRIO Chewable Tablets for Dogs 2.8-5.5 lbs (1.25-2.5 kg)

Simparica TRIO Chewable Tablets for Dogs 2.8-5.5 lbs (1.25-2.5 kg) provide a comprehensive, all-in-one protection against heartworm disease, ticks, fleas, roundworms, and hookworms. This multi-spectrum treatment combines the power of three active ingredients—Sarolaner, Moxidectin, and Pyrantel—to ensure complete protection for your small dog. Simparica TRIO starts killing fleas within 4 hours and eliminates ticks within 8 hours, offering a full month of continuous protection. The chewable tablet is flavored, making it easy to administer as a treat that dogs love.

Indications

Simparica TRIO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis, and for the treatment and control of tick infestations, including black-legged tick (Ixodes scapularis), Gulf Coast tick (Amblyomma maculatum), American dog tick (Dermacentor variabilis), and brown dog tick (Rhipicephalus sanguineus). It is also effective against flea infestations (Ctenocephalides felis) and intestinal worm infections such as roundworms (Toxocara canis) and hookworms (Ancylostoma caninum and Uncinaria stenocephala). Simparica TRIO is suitable for dogs 8 weeks of age and older, weighing 2.8-5.5 lbs (1.25-2.5 kg).

Possible Side Effects

The most commonly reported side effects of Simparica TRIO include vomiting, diarrhea, lethargy, anorexia, and excessive drooling. In rare cases, neurological signs such as tremors, ataxia, and seizures have been reported in dogs taking isoxazoline class drugs, including Sarolaner. Use Simparica TRIO with caution in dogs with a history of seizures or neurological disorders.

Precautions

Sarolaner, Moxidectin, and Pyrantel, the active ingredients in Simparica TRIO, belong to classes of drugs that have been associated with neurologic adverse reactions such as tremors, ataxia, and seizures. Seizures have been reported in dogs taking these drugs, even in those without a prior history of seizures. Therefore, use Simparica TRIO with caution in dogs with a history of seizures or neurological disorders. Simparica TRIO has not been proven effective for puppies less than 8 weeks of age.

Simparica TRIO Protective Measures

• Not for Human Consumption: Simparica TRIO is intended for use in dogs only.
• Use with Caution: Use Simparica TRIO with caution in dogs with a history of seizures or neurological disorders, as the active ingredients have been associated with neurologic adverse reactions such as tremors, ataxia, and seizures.
• Consult Your Vet: Consult your veterinarian before using Simparica TRIO in breeding, pregnant, or lactating females.
• Storage and Handling: Keep the chewable tablet out of reach of pets and children. Do not open the package until required. Avoid eating, drinking, and smoking while administering the dosage. Wash hands with soap and water after handling the chewable.

Contraindications

Simparica TRIO is contraindicated for use in dogs with known hypersensitivity to Sarolaner, Moxidectin, Pyrantel, or any of the product’s components. Do not use Simparica TRIO in dogs that have shown adverse reactions to isoxazoline class drugs. Simparica TRIO is also contraindicated in puppies less than 8 weeks of age.

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