Description
Revolution Topical Solution For Dogs 10.1-20 lbs (5.1-10 kg) contains 60 mg selamectin per tube at 120 mg/mL, formulated by Zoetis for dogs in this mid-small weight band. A single monthly topical application delivers systemic and surface-level parasite control across five indications, from heartworm larval elimination to flea population suppression.
Recommended for
Dogs weighing 10.1–20 lbs (5.1-10 kg), from 6 weeks of age.
Indication/Coverage
For dogs suffering from, or at risk from, mixed parasitic infections, Revolution 10.1–20 lbs addresses the following conditions:
- Flea prevention and treatment: Kills adult fleas (Ctenocephalides felis) and halts egg hatching for one month, targeting both the adult reproductive stage and pre-adult environmental contamination.
- Heartworm prevention: Eliminates Dirofilaria immitis L3 and L4 larvae deposited by mosquitoes in the month prior to application, blocking larval development before adults establish in the pulmonary vasculature.
- Ear mite treatment: Treats Otodectes cynotis infestations in the ear canal; a second monthly dose is required in some dogs to achieve full clearance.
- Sarcoptic mange treatment: Treats Sarcoptes scabiei infestation; a second monthly dose may be necessary, with resolution of pruritus observed in approximately 50% of dogs by day 30 after the first treatment.
- Tick control: Controls Dermacentor variabilis tick infestations on a monthly basis; in heavy infestations, a supplemental dose administered two weeks after the initial application extends coverage before monthly dosing resumes.
Key Benefits
The following attributes are drawn directly from the Zoetis product label for the 60 mg selamectin tube:
- Labeled from 6 weeks: Dogs at the lower boundary of 10.1 lbs from 6 weeks of age fall within the labeled safety profile, with no adverse reactions observed in safety studies at up to 10 times the recommended dose in dogs of this age group.
- Single dose, five indications: One tube covers fleas, heartworm larvae, ear mites, sarcoptic mange, and Dermacentor ticks, consolidating parasite management into a single monthly application without multiple product overlaps.
- Transdermal systemic distribution: Selamectin absorbs through the skin and circulates systemically, enabling activity against internal parasites such as immitis larvae that oral surface-acting products cannot reach.
- Sustained flea egg suppression: Revolution prevents viable flea egg development for a full 30-day interval, addressing environmental reinfestation rather than surface-level adult kill alone.
- Supplemental tick dosing protocol: For dogs in high variabilis burden environments, a second dose at two weeks following initial application extends tick control before the monthly schedule resumes, per the labeled dosing protocol.
- Monthly schedule alignment across indications: Heartworm prevention, flea control, and tick management all operate on the same 30-day interval, requiring no separate tracking for individual parasite categories.
- Topical delivery for tablet-resistant dogs: Administration to the skin at the base of the neck bypasses oral refusal, incomplete ingestion, or vomiting-related dose loss that can occur with chewable antiparasitic formats.
Caution
Hazards to Humans
Revolution is flammable and irritating to eyes. Avoid contact with skin and clothing during application, wash hands thoroughly afterward, and keep the product away from open flame. Do not allow children to handle the tubes. Keep Revolution clear of food preparation areas and surfaces.
Hazards to Domestic Animals
Revolution is formulated for external application only and must not be ingested. This tube is labeled for dogs weighing 10.1–20 lbs (5.1-10 kg) from a minimum age of 6 weeks; do not administer to dogs below either threshold. Dogs that are sick, debilitated, aged, should be evaluated by a veterinarian before treatment. Individual sensitivity has been documented in avermectin-sensitive collies at the standard topical dose. Do not combine with other macrocyclic lactone products without prior veterinary review.
Possible Side Effects
Monitor your dog closely after each Revolution application, particularly following the first dose in a new treatment course. Post-approval adverse event reports submitted to the FDA/CVM document the following reactions:
Application site reactions include transient alopecia, erythema, pruritus, vesicles, blisters, and excoriations, all of which are generally self-limiting and localized to the treated area. Gastrointestinal signs reported encompass vomiting, diarrhea or loose stool, and hypersalivation. Systemic signs documented include lethargy, anorexia, generalized pruritus, seizures, tremors, ataxia, and dermatitis.
Contact a veterinarian immediately if any of these signs appear.















Revolution provides reliable protection for my Newfoundland dog in Alberta’s varied landscapes.
As someone with multiple pets, I was looking for an efficient way to manage their heartworm prevention. This product, coupled with Anipetshop’s bulk ordering option, has been a perfect solution.
I’m impressed by how quickly the product arrived after ordering from Anipetshop.
Finding reliable heartworm prevention without a vet visit was a real challenge in my area. Discovering Anipetshop was a relief – they offer the same trusted products with a hassle-free ordering process.
The fact that Revolution protects against multiple parasites makes it great value for money.